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Abstract
Among the reported high-speed counter-current chromatographic (CCC) separations, most of the separations have been achieved with a relatively long timeframe while only few showed characteristics of rapid separation. In the present article, rapid separations by HSCCC are reviewed and a new term “flash counter-current chromatography” (FCCC) is suggested to distinguish the rapid CCC separations from other methods. FCCC was defined as a separation possess in which the flow rate of mobile phase (mL) is equal to or greater than the square of the diameter of the column tubing (mm). The term may pilot the manufacturers of modern CCC instruments to improve the design of the apparatus and guide the CCC users to pursue rapid separations.
Notes
Abbreviation: TID, tubing inner diameter; MF, flow rate of mobile phase; RS, rotation speed of column; TBME, methyl tert-butyl ether.
/: no data was given in the paper.
Abbreviation: TID, tubing inner diameter; MF, flow rate of mobile phase; RS: rotation speed of column; TBME, methyl tert-butyl ether.
Abbreviation: TID, tubing inner diameter; MF, flow rate of mobile phase; RS: rotation speed of column; TBME, methyl tert-butyl ether.
a At any retention percentage of stationary phase.
b At 50% retention percentage of stationary phase.
/: no data was given in the paper.