Response surface methodology optimizing the adsorptive removal of azithromycin using mesoporous silica SBA-15: Mechanism, thermodynamic, equilibrium, and kinetics modeling studies

Abstract

The objective of this research was to study an effective adsorbent for removing azithromycin (AZT) from industrial wastewater. AZT is an antibiotic used for many diseases remedy, but it is a pollutant to our environment; therefore, its residual should be removed from wastewater. The mesoporous SBA-15 silica as an efficient adsorbent was prepared by the hydrothermal method. The surface of mesoporous SBA-15 plays a significant role in the removal process; therefore, the characterization of the adsorbent was accomplished by several techniques. The batch system has been used, and the effect of four essential variables: pH (3-10), drug concentration (20-200 mg L⁻¹), sorbent weight (0.2-2 g L⁻¹), and temperature (20-40 °C) were investigated on the AZT removal efficiency by response surface methodology (RSM). The isotherm results were found to be in proper compliance with the isotherm model of Freundlich. In the kinetics part of this study, the experimental outcomes were fitted to the equation model of pseudo-second-order. The calculation of thermodynamic parameters shows that the removal process is spontaneous and endothermic. Upon the results, the vast surface area, the active functional groups, reusability, stability, and inexpensively make the mesoporous SBA-15 a suitable candidate for removal of AZT and similar antibiotics.

Keywords:

• Characterization
• Antibiotic removal
• RSM optimization
• Isotherm models
• kinetics models

Additional information

Funding

The authors acknowledge the deputy of the Shahid Chamran University of Ahvaz and The University of Tehran for the funding and this research.