Granisetron vs. Granisetron and Dexamethasone on The Reduction of Postoperative Nausea and Vomiting (PONV) After Caesarean Section With Intrathecal Morphine: A Randomised Controlled Trial

Figures & data

Table 1. Patients’ baseline characteristics

Variable	Mean (SD)		P-value
	Group A Granisetron + Dexamethasone (n = 57)	Group B Granisetron (n = 57)
Age (years)	31.8 (4.8)	31.3 (5.3)	0.542
Weight (kg)	70.5 (14.5)	71.4 (12.4)	0.715
Height (m)	1.54 (0.06)	1.55 (0.06)	0.442
BMI	29.3 (4.97)	29.2 (4.62)	0.827
Gravidity	2.7 (1.4)	3.0 (1.9)	0.225
Parity	1.5 (1.2)	1.7 (1.5)	0.452
APFEL Score, n (%)**
1	0	0	-
2	0	0	-
3	57(50)	57(50)	-
4	0	0	-
ASA Physical Status, n (%)**
I	29 (50.9)	23 (40.4)	0.347
II	28 (49.1)	34 (59.6)

Independent T-Test

**Chi-square Test

Table 2. Incidence of PONV at 1, 4, 8, 12 and 24-hour postoperatively

Variable	Frequency, n (%)		X^2 (df)	P-value
	Group A Granisetron + Dexamethasone (n = 57)	Group B Granisetron (n = 57)
Nausea at 1-hour	2 (3.5)	2 (3.5)	0 [1]	0.999
Retching at 1-hour	2 (3.5)	2 (3.5)	0 [1]	0.999
Vomiting at 1-hour	2 (3.5)	2 (3.5)	0 [1]	0.999
Use antiemetic at 1-hour	2 (3.5)	2 (3.5)	0 [1]	0.999
Nausea at 4-hour	5 (8.8)	4 [7]	0.121 [1]	0.999
Retching at 4-hour	3 (5.3)	2 (3.5)	0.209 [1]	0.999
Vomiting at 4-hour	3 (5.3)	3 (5.3)	0 [1]	0.999
Use antiemetic at 4-hour	3 (5.3)	3 (5.3)	0 [1]	0.999
Nausea at 8-hour	2 (3.5)	2 (3.5)	0 [1]	0.999
Retching at 8-hour	2 (3.5)	1 (1.8)	0.342 [1]	0.999
Vomiting at 8-hour	3 (5.3)	3 (5.3)	0 [1]	0.999
Use antiemetic at 8-hour	3 (5.3)	3 (5.3)	0 [1]	0.999
Nausea at 12-hour	0	0	-	-
Retching at 12-hour	0	1 (1.8)	1.009 [1]	0.999
Vomiting at 12-hour	0	0	-	-
Use antiemetic at 12-hour	0	0	-	-
Nausea at 24-hour	0	0	-	-
Retching at 24-hour	0	0	-	-
Vomiting at 24-hour	0	0	-	-
Use antiemetic at 24-hour	0	0	-	-

*Chi-square test

Figure 1. Incidence of PONV between Group A and Group B

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