COMPARATIVE STUDY BETWEEN THE EFFECT OF VOLUME-CONTROLLED VENTILATION AND PRESSURE CONTROLLED VENTILATION VOLUME GUARANTEED ON GAS EXCHANGE AND RESPIRATORY DYNAMICS DURING ONE-LUNG VENTILATION

Figures & data

Table 1. Demographic data

	VCV (n = 15)	PCV-VG (n = 15)	P
Sex
Male	9(60.0%)	8(53.3%)	0.713
Female	6(40.0%)	7(46.7%)
Age (years), mean ± SD.	34.73 ± 9.76	34.33 ± 8.61	0.906
BMI (kg/m^2), mean ± SD.	23.86 ± 1.27	23.70 ± 1.04	0.709
Duration of surgery (min), mean ± SD.	85.13 ± 6.19	86.0 ± 5.92	0.698
Type of surgery			0.896
Sympathectomy	4	3
L.N Biopsy	5	5
Wedge Resection	3	3
Chest wall tumor	2	1
Segmentectomy	1	3

Statistically significant at p ≤ 0.05.

Table 2. Oxygenation parameters and haemodynamic data in both groups. Data are expressed as mean ± SD.Time points: before induction of anaesthesia as a baseline (T₀); during two lung ventilation (T₁); 30 min after one lung ventilation (T₂); one hour after OLV (T3); 20 min after resuming TLV (T4); 6; 12; and 24 hours after surgery (T5, T6, and T7). PCV-VG, pressure-controlled ventilation volume guaranteed; VCV, volume-controlled ventilation; PaO₂, arterial blood oxygen tension; PaCO₂, arterial blood carbon dioxide tension; FiO₂, fraction of inspired oxygen; SaO₂, arterial oxygen saturation; HR, heart rate; MAP, mean arterial pressure; CVP, central venous pressure. $ P < 0.05 within the PCV-VG group; # P < 0.05 within the VCV group

HR

73.07 ± 6.51

82.40^# ±5.57

87.93^# ±5.32

87.87^# ±5.44

86.0^# ±5.03

82.67^# ±4.91

81.0^# ±5.69

79.0^# ±4.80

74.67 ± 7.14

84.20^$ ±5.44

88.0^$ ±4.64

88.47^$ ±4.67

85.73^$ ±3.59

82.27^$ ±4.73

80.60^$ ±5.18

78.93 ± 5.40

MAP

86.07 ± 4.85

91.07^# ±4.15

92.27^# ±4.68

92.87^# ±3.89

88.93 ± 5.50

86.93 ± 4.43

86.20 ± 4.25

85.27 ± 5.44

85.87 ± 4.93

90.40^$ ±4.50

90.27 ± 6.99

91.53^$ ±4.90

87.80 ± 4.20

86.13 ± 4.05

84.87 ± 4.10

84.20 ± 5.54

CVP

7.27^# ±1.03

8.67^# ±0.72

10.47^# ±0.83

11.0^# ±0.85

10.6^# ±0.74

10.13^# ±0.74

10.13^# ±0.92

9.53^# ±0.64

7.20 ± 0.77

8.60^$ ±0.63

10.47^$ ±0.83

11.13^$ ±0.92

10.4^$ ±0.63

9.93^$±0.80

9.87^$ ±0.99

9.13^$± 1.06

pH

7.40 ± 0.02

7.41 ± 0.02

7.41 ± 0.01

7.40 ± 0.02

7.41 ± 0.02

7.40 ± 0.01

7.40 ± 0.02

7.40 ± 0.02

7.39 ± 0.01

7.41 ± 0.02

7.41 ± 0.02

7.39 ± 0.02

7.40 ± 0.02

7.41 ± 0.02

7.41 ± 0.02

7.40 ± 0.02

PaO2

86.07 ± 2.19

403.5^# ±10.66

196.9^# ±5.66

187.5^# ±5.64

392.3^# ±11.2

84.6^#±2.20

84.8^#±1.86

84.8 ± 2.04

86.93 ± 1.94

406.2^$±10.18

199.9^$ ±3.78

190.5^$ ±4.16

399.1^$ ±9.53

85.20 ± 2.21

85.20^$ ±1.90

85.13 ± 2.29

PaCO2

40.20 ± 1.82

37.80^# ±1.08

37.60^# ±1.24

38.60 ± 0.83

37.87 ± 1.30

40.60 ± 2.32

40.07 ± 2.55

41.07 ± 2.15

41.20 ± 2.21

37.73^$ ±1.22

37.67^$ ±1.29

38.07^$ ±1.16

38.47^$ ±1.25

40.33 ± 2.55

40.07 ± 2.31

39.87 ± 2.26

SaO2

97.60 ± 0.74

99.0^# ±0.0

99.0^# ± 0.0

98.8^# ±0.41

99.0^# ±0.0

97.40 ± 0.91

97.47 ± 0.83

97.73 ± 0.70

97.47 ± 0.74

99.0^$ ±0.0

99.0^$ ±0.0

98.93^$ ±0.26

99.0^$ ±0.0

97.53 ± 0.83

97.33 ± 0.62

97.53 ± 0.74

PaO2/FiO2

409.5 ± 10.31

403.5^#±10.66

196.9^# ±5.66

187.5^# ±5.64

392.3^# ±11.2

402.3^#±10.57

403.7^# ±8.39

403.4^# ±9.77

413.8 ± 9.30

406.2^$±10.18

199.9^$ ±3.78

190.5^$ ±4.16

399.1^$ ±9.53

405.3 ± 10.67

405.3^$ ±9.08

404.9 ± 11.09

VARIABLES

T0

T1

T2

T3

T4

T5

T6

T7

T0

T1

T2

T3

T4

T5

T6

T7

VCV

PCV-VG

Figure 1. Flow chart of patients

Figure 2. Comparison between the two studied groups

Figure 3. Comparison between the two studied groups according to according to P_peak(cm/H₂O) according to P_mean(cm/H₂O)

Figure 4. Comparison between the two studied groups

Figure 5. Comparison between the two studied according to C_dyn (ml/cm H₂O) groups according to TNFα (pg/ml)

Figure 6. Correlation between TNFα (pg/ml) and P _peak (cm/H₂O)

Figure 7. Correlation between TNFα (pg/ml) and C_dyn (ml/cmH₂o)