Effectiveness of adding magnesium sulfate to bupivacaine in ultrasound guided serratus anterior plane block in patients undergoing modified radical mastectomy

Figures & data

Figure 1. Flow diagram of involved patients in the study.

Table 1. Patients’ data and duration of surgery.

	B group		BM group		P value
Age (in years) Range Mean ± SD	22–62 47.28 ± 9.95		21–61 44.70 ± 10.17		0.128 N.S.
ASA	No	%	No	%	0.253 N.S.
I II	24 16	60.0 40.0	21 19	52.5 47.5
BMI Range Mean ± SD	21.1–33.2 27.53 ± 3.03		21.1–34.2 28.47 ± 4.20		0.128 N.S.
Duration of surgery (in minutes) Range Mean ± SD	70–80 75.88 ± 4.22		70–80 75.38 ± 4.29		0.300 N.S.

N.S.: Not significant

Data are presented as range, mean ± SD or No. (%)

Figure 2. HR changes in both groups at different measurement times.

Figure 3. MAP changes in both groups at different measurement times.

Figure 4. Oxygen saturation changes in both groups at different measurement times.

Table 2. VAS at rest and with movement at different postoperative times.

	B group		BM group
	At rest	With movement	At rest	With movement	P value
Timing postoperative	Median(Range)		Median(Range)		At rest	With movement
At 30min	1.0(0–2)	2.0(1–3)	1.0(0–2)	2.0(1–3)	0.500	0.342
At 2h	1.0(1–2)	3.0(2–3)	1.0(1–2)	2.0(1–3)	0.500	0.005*
At 4h	2.0(1–3)	2.0(2–3)	1.0(1–2)	2.0(1–3)	0.002*	0.017*
At 8h	2.5(1–4)	3.0(2–5)	2.0(1–3)	2.0(1–3)	0.049*	0.001*
At 12h	3.0(2–5)	4.0(2–6)	2.5(1–4)	3.5(1–5)	0.003*	0.009*
At 24 h	3.0(1–5)	4.0(2–6)	3.0(1–4)	3.0(1–5)	0.030*	0.001*

* P ≤ 0.05 is significant.

Table 3. Timing for the first rescue analgesia and total dose of nalbuphine in both groups.

	B group	BM group	P
Time till the first rescue analgesia in h Range Mean± SD	6–10 8.13±1.38	9–15 11.73±1.91	0.001*
Total dose of nalbuphine in mg Range Mean± SD	10–20 15.50±3.89	5–15 9.63±4.44	0.001*

Data are expressed as range – mean ± SD

* P ≤ 0.05 is significant.

Table 4. Postoperative nausea and vomiting, complication and patient satisfaction in both groups.

	B group		BM group		P value
	No	%	No	%
PONV score 0 1 2	14 16 10	35 40 25	22 18 0	55 45 0	0.021*
Antiemetic ondansetron	5	12.5	3	7.5	0.106 N.S.
Complication and side effect Hematoma Hypotension Respiratory depression	2 0 0	5.0 0.0 0.0	2 0 0	5.0 0.0 0.0	1.00 N.S.
Patient satisfaction					0.001*
Very unsatisfied	11	27.5	0	0
Unsatisfied	7	17.5	8	20
Neutral	12	30	14	35
Satisfied	10	25	9	22.5
Very satisfied	0	0	9	22.5

Data are presented as range, mean ± SD or No. (%)

* P ≤ 0.05 is significant.