Comparative Study Between Desflurane and Sevoflurane Regarding Haemodynamics and Recovery Profiles in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy

Figures & data

Figure 1. CONSORT flow diagram. Enrolment, randomization and allocation of the study subjects.

Table 1. Demographic and operative data.

Parameters	Group D (n = 25)	Group S (n = 25)	P value
Age (years)	31.60 ± 5.60	30.36 ± 6.14	= 0.459
Gender (M/F)	10/15	9/16	= 0.771
Weight (kg)	127.8 ± 27.90	124.4 ± 18.6	= 0.615
Height (cm)	166.3 ± 7.78	163.9 ± 7.59	= 0.267
BMI (kg/m^2)	46.02 ± 8.07	46.29 ± 6.16	= 0.892
Duration of anaesthesia (minutes)	116.2 ± 26.17	115.8 ± 23.53	= 0.959
Duration of surgery (minutes)	104.3 ± 23.87	103.5 ± 22.46	= 0.903

Values are expressed as mean standard deviation (SD) – t: Student t-test – χ²: Chi square test. p: p value for comparing between the two studied groups. *: Statistically significant at p ≤ 0.05.

Abbreviation: BMI, body mass index.

Figure 2. Comparison between the two studied groups according to haemodynamic parameters (a) heart rate, (b) mean arterial pressure and (c) cardiac index. Results are presented as mean ± SD.

Figure 3. Comparison between the two studied groups according to MAC_EN.

Table 2. Comparison between the two studied groups according to immediate, intermediate recovery, length of PACU stay.

Parameters	Group D	Group S	P value
Time to reach fully awake entropy (minutes)	1.80 ± 0.63	3.64 ± 0.86	<0.001
Time to eye opening (minutes)	4.83 ± 1.59	8.18 ± 2.11	<0.001
Time to extubation of trachea (minutes)	5.59 ± 1.71	8.89 ± 2.05	<0.001
Following simple commands (minutes)	6.21 ± 1.70	9.72 ± 2.05	<0.001
Orientation to person and place (minutes)	7.11 ± 1.63	10.96 ± 2.06	<0.001
Modified Aldrete Score (MAS):
Upon arrival at PACU.	8.52 ± 0.59	7.96 ± 0.84	= 0.009
After 5 minutes.	9.12 ± 0.67	8.64 ± 0.86	= 0.032
After 10 minutes.	9.60 ± 0.50	9.32 ± 0.75	= 0.127
DSST (minutes)	23.88 ± 3.99	33.94 ± 3.28	<0.001
Length of PACU stay (minutes)	29.50 ± 3.45	37.65 ± 3.30	<0.001

SD: Standard deviation t: Student t-test U: Mann Whitney test p: p value for comparing between the two studied groups DSST: Digit Symbol Substitution Test. *: Statistically significant at p ≤ 0.05. PACU: Post Anaesthesia Care Unit.