Effect of magnesium levels on mean tissue perfusion during and after bariatric surgeries: A randomised control trial

Figures & data

Figure 1. Masimo perfusion index technology (MightySat® Rx Fingertip Pulse Oximeter).

CONSORT flowchart of the enrolled patients.

Table 1. Comparison between the two studied groups according to demographic data, analgesic consumption, time of analgesia and complications.

	Group M (n = 30)	Group C (n = 30)	Test of Sig.	P
Age (years)
Mean ± SD.	33.6 ± 7.9	37 ± 10.4	t= 1.425	0.160
Gender
Male	15 (50%)	14 (46.7%)	χ^2= 0.067	0.796
Female	15 (50%)	16 (53.3%)
BMI (kg/m2)
Mean ± SD.	39.85 ± 2.3	41.1 ± 2.5	t= 1.954	0.056
VAS score (cm)
30 min.	2.90 ± 1.37	3.90 ± 1.67	299.0*	0.022*
90 min.	2.27 ± 1.01	2.80 ± 1.10	316.5*	0.038*
2 Hr.	2.53 ± 0.82	2.70 ± 0.53	416.0	0.540
4 Hr.	2.97 ± 0.81	5.03 ± 0.67	22.50*	<0.001*
8 Hr.	3.17 ± 1.29	2.40 ± 0.77	291.0*	0.014*
Analgesic consumption (morphine) (mg) at 8 hr.
Mean ± SD.	15.7 ± 4.55	25.25 ± 6.1	t= 6.874*	<0.001*
Time of analgesia
30 min.	11 (36.7%)	16 (53.3%)	χ^2 = 1.684	0.194
90 min.	5 (16.7%)	9 (30%)	χ^2 = 1.491	0.222
2 hr.	1 (3.3%)	0 (0%)	χ^2 = 1.017	^FEp = 1.000
4 hr.	7 (23.3%)	29 (96.7%)	χ^2 = 33.611*	<0.001*
8 hr.	14 (46.7%)	1 (3.3%)	χ^2 = 15.022*	<0.001*
Complications
Nausea & Vomiting	9 (30%)	16 (53.3%)	χ^2 = 3.360	0.067
PO hypotension	3 (10%)	1 (3.3%)	χ^2 = 1.071	^FEp = 0.612
PO neurological	1 (3.3%)	0 (0%)	χ^2 = 1.017	^FEp = 1.000

SD: Standard deviation t: Student t-test χ²: Chi square test.

FE: Fisher Exact.

p: p value for comparing between the two studied groups.

*: Statistically significant at p ≤ 0.05.

Figure 2. Comparison between the two studied groups according to HR (b/min).

Figure 3. Comparison between the two studied groups according to MAPB (mmHg).

Table 2. Comparison between the two studied groups according to PI (%), alkaline phosphatase, sgot, sgpt, and magnesium levels.

	Group M (n = 30)	Group C (n = 30)	T	p
PI (%)
Immediately after induction and before surgery	4.02 ± 0.90	3.70 ± 1.04	1.261	0.212
30 min.	4.24 ± 0.81	4.01 ± 0.74	1.165	0.249
1 hr.	4.05 ± 0.83	3.64 ± 0.64	2.128*	0.038*
2 hr.	4.16 ± 0.91	3.79 ± 0.64	1.820	0.074
4 hr.	4.41^# ±0.79	3.64 ± 0.76	3.827*	<0.001*
6 hr.	3.88 ± 0.71	3.21^# ±0.83	3.353*	0.001*
8 hr.	4.37^# ±0.67	3.72 ± 0.66	3.771*	<0.001*
Alkaline phosphatase (IU/L)
Pre	44.69 ± 11.85	41.43 ± 12.85	1.021	0.311
Post	48.76 ± 12.19	47.51 ± 11.69	0.406	0.686
Magnesium level (mg/dL)
Pre	2.06 ± 0.19	1.98 ± 0.17	1.826	0.073
Post	2.17^# ±0.15	1.93 ± 0.15	6.452*	<0.001*
SGOT (U/L)
Pre	20.01 ± 3.53	21.76 ± 3.75	1.865	0.067
Post	59.92 ± 9.34	76.21 ± 10.29	6.420*	<0.001*
SGPT (U/L)
Pre	25.19 ± 4.65	23.19 ± 3.30	1.926	0.059
Post	65.13 ± 6.19	72.43 ± 6.87	4.326*	<0.001*

Data was expressed using Mean ± SD.SD: Standard deviation t: Student t-test.

p: p value for comparing between the two studied groups.

*: Statistically significant at p ≤ 0.05 #: Significant with before surgery.

Table 3. Comparing the two studied groups according to RASS score.

RASS score	Group M (n = 30)	Group C (n = 30)	U	P
2 hr.
Mean ± SD.	0.10 ± 1.30	0.80 ± 1.24	317.0*	0.038*
Median (Min. – Max.)	−0.50 (−1–2)	1 (−1–2)
4 hr.
Mean ± SD.	0.30 ± 0.60	0.30 ± 0.79	447.0	0.957
Median (Min. – Max.)	0 (0–2)	0 (−1–2)
6 hr.
Mean ± SD.	0.43 ± 0.57	1.47 ± 0.57	119.5*	<0.001*
Median (Min. – Max.)	0 (0–2)	1.50 (0–2)
8 hr.
Mean ± SD.	0.57 ± 0.77	0.63 ± 0.56	399.0	0.402
Median (Min. – Max.)	0 (0–2)	1 (0–2)
At discharge
Mean ± SD.	−0.57 ± 0.50	−0.53 ± 0.51	435.0	0. 827
Median (Min. – Max.)	−1 (−1–0)	−1 (−1–0)

SD: Standard deviation, U: Mann Whitney test, p: p value for comparing between the two studied groups, *: Statistically significant at p ≤ 0.05.