Premedication with Oral Midazolam Suppress Fentanyl- Induced Cough in Children: A Randomized Double-Blind Trial

Figures & data

Figure 1. CONSORT flowchart of the enrolled patients.

Table 1. Demographic data and baseline data of the studied groups.

		Group C (n = 40)	Group MID 0.5 (n = 40)	Group MID 0.7 (n = 40)	P value
Age (years)		4.39 ± 2.99	4.38 ± 2.67	5.00 ± 3.41	0.63
Sex	Male	17 (56.67%)	17 (56.67%)	16 (53.33%)	0.956
	Female	13 (43.33%)	13 (43.33%)	14 (46.67%)
Weight (kg)		18.84 ± 7.96	20.53 ± 1.27	18.35 ± 7.11	0.47
Heart rate		123.78 ± 20.27	121.79 ± 9.15	124.24 ± 16.93	0.803
SpO2		97.27 ± 1.52	124.32 ± 5.2	97.60 ± 1.72	0.07

Data are presented as mean ± SD or frequency (%), SpO₂: oxygen saturation.

Table 2. Incidence, onset, and severity of FIC in the studied groups.

		Group C (n = 40)	Group MID 0.5 (n = 40)	Group MID 0.7 (n = 40)	P value
Incidence of FIC		39 (97.5%)	36 (90%)	15 (6%)	0.001
Onset (seconds)		5.57 ± 2.87	6.9 ± 2.07	6.94 ± 2.95	0.99
Severity	Mild	10 (25%)	30 (75%)	38 (95%)	0.001
	Moderate	2 (5%)	8 (20%)	2 (5%)
	Severe	28 (70%)	2 (5%)	0%

Data are presented as mean ± SD or frequency (%).