Ultrasound continuous erector spinae catheter versus paravertebral catheter for pain management in modified radical mastectomy for cancer patients: A randomized double-blind

Figures & data

Figure 1. CONSORT flowchart of the enrolled patients.

Table 1. Demographic data, side of the operation and duration of block performance and surgery between groups.

		Group ESPB (n=35)	Group PVB (n=35)	P value
Age (years)		46.49 ± 12	49.17 ± 9.69	0.307
Weight (kg)		85.49 ± 12.7	83.2 ± 14.36	0.483
Height (m)		1.69 ± 0.05	1.69 ± 0.06	0.710
BMI (kg/m^2)		30.15 ± 5.11	29.21 ± 5.75	0.471
ASA physical status	II	16 (45.71%)	18 (51.43%)	0.632
	III	19 (54.29%)	17 (48.57%)
Side of the operation	Right	16 (45.71%)	22 (62.86%)	0.150
	Left	19 (54.29%)	13 (37.14%)
Duration of block performance (min)		21.77 ± 4.12	33.14 ± 5.14	<0.001*
Duration of surgery (min)		147 ± 18.16	149.86 ± 19.5	0.528

Data are presented as mean ± SD or frequency (%). BMI: body mass index, ASA: American Society of Anesthesiologists. p value less than 0.05 statistically significant value.

Figure 2. Intraoperative and postoperative (a) heart rate, (b) mean arterial blood pressure, and (c) oxygen saturation measurements of the studied groups.

Table 2. VAS measurements at rest and movement of the studied groups.

	Group ESPB (n=35)	Group PVB (n=35)	P value
At rest
PACU	1 (0–2)	1 (0–2)	0.540
2h	2 (1–2)	2 (1–2)	0.823
4 h	2 (1–2)	2 (2–2)	0.762
6 h	2 (2–2)	2 (2–2)	0.418
8 h	2 (2–2)	2 (2–2)	0.831
12 h	2 (1–2)	2 (2–2)	0.927
18 h	3 (2–2)	2 (2–2)	0.509
24 h	3 (2–2)	3 (2–2)	0.653
36 h	3 (2–3)	3 (2–3)	0.908
48 h	3 (2–3)	3 (2–3)	0.625
At movement
PACU	2 (2–3)	2 (2–3)	0.945
2h	3 (2–3)	2 (2–3)	0.822
4 h	2 (2–3)	3 (2–3)	0.684
6 h	3 (2–3)	3 (2–3)	0.920
8 h	3 (2–3)	3 (2–3)	0.571
12 h	3 (2–3)	3 (2–3)	0.857
18 h	3 (2–3)	3 (2–3)	0.842
24 h	3 (2–3)	3 (2–3)	0.657
36 h	3 (3–3)	3 (3–3)	0.683
48 h	3 (3–3)	3 (3–3)	0.704

Data are presented as median (IQR). PACU: post-anesthesia care unit.

Table 3. Intraoperative fentanyl and postoperative morphine consumption of the studied groups.

	Group ESPB (n=35)	Group PVB (n=35)	P value	95% CI
Number of patients required intraoperative fentanyl	4 (11.43%)	3 (8.57%)	0.690	0.28:6.66
Number of patients who required morphine in 1^st 48 h postoperative	6 (17.14%)	7 (20%)	0.759	0.25:2.77
Total morphine consumption in 1^st 48 h postoperative (mg)	1.54 ± 3.74	1.63 ± 3.44	0.921	−1.8: 1.63
	(n=6)	(n=7)
Time to 1^st request analgesia (h)	26 ± 11.8	25.71 ± 10.8	0.964	−5.11: 5.68

Data are presented as mean ± SD or frequency (%).

Table 4. Postoperative complications between groups.

	Group ESPB (n=35)	Group PVB (n=35)	P value
Pneumothorax	0 (0%)	1 (2.86%)	1.00
Hematoma	0 (0%)	0 (0%)	–
Motor and neurologic deficit	0 (0%)	0 (0%)	–

Data are presented as frequency (%).