Analgesic effect of adding modified pectoral nerve block to serratus anterior plane block in modified radical mastectomy: Randomized double-blinded trial

Figures & data

Figure 1. CONSORT flow diagram.

Figure 2. Serratus black with needle visualization.

Figure 3. Pecs block with needle visualization.

Table 1. Baseline characteristics of the two studied groups.

	SAPB Group (n = 30)	Combined Group (n = 30)	p-value
Age (years)	48.8 ± 10.8	47.1 ± 8.9	0.507
Weight (kg)	79.9 ± 11.7	80.9 ± 9.3	0.535
Height (m)	1.67 ± 0.07	1.69 ± 0.06	0.357
ASA Class (II/III)	26/4	27/3	1.000

Data are presented as mean ± SD.

Figure 4. Changes in heart rate in the intraoperative period.

Figure 5. Changes in the mean arterial pressure in the intraoperative period.

Figure 6. Changes in heart rate in the postoperative period.

Figure 7. Changes in the mean arterial pressure in the postoperative period.

Table 2. Analgesic profile of the two studied groups.

	SAPB Group (n = 30)	Combined Group (n = 30)	p-value
Intraoperative fentanyl consumption (µg)	160.0 ± 53.2	130.7 ± 44.4	0.024
Duration of analgesia (h)	4 (2–8)	4 (2–12)	0.454
Postoperative morphine consumption (mg)	6 (3–9)	1.5 (0–6)	0.005

Data are presented as mean ± SD or median (range).

Table 3. Postoperative numerical rating scale score at rest in the two groups.

	SAPB Group (n = 30)	Combined Group (n = 30)	p-value
Immediate	2 (1–2)	0 (0–2)	0.003
After 2 hours	2 (1–2)	0 (0–2)	0.005
After 4 hrs.	2 (1–3)	1 (0–2)	0.004
After 8 hrs.	2 (1–3)	1 (0–2)	0.015
After 12 hrs.	2 (1–3)	1 (0–2)	0.043
After 18 hrs.	2 (2–3)	2 (1–2)	0.009
After 24 hrs.	2 (2–3)	2 (1–2)	0.007

Data are presented as median (interquartile range).

Table 4. Postoperative numerical rating scale score during movement in the two groups.

	SAPB Group (n=30)	Combined Group (n=30)	p-value
Immediate	2 (1–3)	1 (0–2)	0.003
After 2 hours	2 (2–3)	1 (0–3)	0.005
After 4 hrs.	3 (2–3)	2 (1–2)	0.001
After 8 hrs.	3 (2–3)	2 (1–2)	<0.001
After 12 hrs.	3 (2–3)	2 (1–3)	0.005
After 18 hrs.	3 (3–3)	2 (1–3)	0.001
After 24 hrs.	3 (2–3)	2 (2–3)	<0.001

Data are presented as median (interquartile range).

Table 5. Adverse events between both groups.

	SAPB Group (n=30)	Combined Group (n=30)	p-value
PONV
No	16 (53.33%)	20 (66.67%)	0.572
Mild	11 (36.67%)	8 (26.67%)
Moderate	3 (10.00%)	2 (6.67%)
Urine retention	1 (3.3%)	1 (3.3%)	1.000
Block complications (Intramuscular hematoma)	5 (16.67%)	0 (0%)	0.052

Data are presented as number (%).

PONV: Postoperative nausea and vomiting.