Subclinical hypothyroidism: association with cardiovascular risk factors and components of metabolic syndrome

Figures & data

Table 1. Anthropometric measurements and blood pressure in SH patients and control group.

	SH patients	Control group
Parameters	Mean ± SD Md	Mean ± SD Md
Body mass index (kg/m^2)	28.0 ± 3.35 (28.00)*	26.37 ± 2.31 (26.00)
Waist circumference (cm)	88.00 ± 11.66 (87.50)	89.20 ± 9.76 (88.00)
Systolic blood pressure (mmHg) (SBP)	130.00 ± 12.66 (130.00)	125.67 ± 8.88 (125.00)
Diastolic blood pressure (mmHg) (DBP)	84.83 ± 10.87 (85.00)^‡	74.33 ± 8.98 (75.00)

SD – standard deviation; Md – median; *p < 0.05, ^‡p < 0.001.

Table 2. Lipid profile and metabolic parameters in SH patients and control group.

	SH patients	Control group
Parameters	Mean ± SD Md	Mean ± SD Md
Total cholesterol (mmol/l)	5.40 ± 0.62 (5.40)*	5.03 ± 0.19 (5.00)
LDL cholesterol (mmol/l)	3.35 ± 0.44 (3.40)	3.17 ± 0.39 (3.00)
HDL cholesterol (mmol/l)	1.26 ± 0.23 (1.30)	1.45 ± 0.17 (1.50)
Triglycerides (mmol/l)	2.16 ± 0.56 (2.10)*	1.89 ± 0.24 (1.85)
Fasting glycaemia (mmol/l)	4.91 ± 0.97 (4.90)	4.95 ± 1.22 (4.95)
Fasting insulinemia (mU/l)	15.52 ± 1.99 (15.50)*	12.22 ± 2.05 (12.00)
HOMA-IR	2.99 ± 3.0 (3.00)	2.64 ± 2.1 (2.60)

SD – standard deviation; Md – median; *p < 0.05.

Table 3. Traditional cardiovascular risk factors in SH patients and control group.

	SH patients		Control group
Parameters	n	%	n	%
Blood pressure ≥ 140/90 mmHg	20	33.33%*	4	6.67%
Total cholesterol (TC) ≥ 5.2 mmol/l	38	63.33%*	18	30.00%
≥ 6.2 mmol/l	8	13.33%	3	5.00%
LDL cholesterol ≥ 3.4 mmol/l	32	53.33%	26	43.33%
≥ 4.1 mmol/l	2	3.33%	1	1.66%
Triglycerides ≥ 1.7 mmol/l	50	83.33%	48	80.00%
≥ 2.3 mmol/l	26	43.33%^‡	6	10.00%
TC/HDL ratio > 5	16	26.67%^†	3	5.00%
LDL/HDL ratio > 3.5	19	16.67%	2	3.33%

*p < 0.05, ^†p < 0.01, ^‡p < 0.001.

n – number of patients.

Table 4. Metabolic syndrome parameters in SH patients and control group.

	SH patients	Control group
MetS parameters	n (%)	n (%)
Abdominal obesity	28 (46.67%)	26 (43.33%)
Blood pressure ≥130/≥85 mmHg	22 (36.67%)*	6 (10.00%)
Low HDL cholesterol ‡	38 (63.33%)*	20 (33.33%)
High triglycerides, TG ≥ 1.7 mmol/l	50 (83.33%)	48 (80.00%)
Fasting plasma glucose, FPG ≥ 5.6 mmol/l	8 (13.33%)	6 (10.00%)

*p < 0.05.

‡ Low HDL cholesterol in men ≤ 1.03 mmol/l, in women ≤1.3 mmol/l.

n – number of patients.