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Biotechnology & Biotechnological Equipment Volume 34, 2020 - Issue 1
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Research Article

Protective effects of Naoxintong Capsule on rats with blood stasis syndrome

Wei-jian Zhanga Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaView further author information
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Wei-wei Sua Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaView further author information
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Qing-wei Lina Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaView further author information
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Zeng-hao Yana Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaView further author information
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Yong-gang Wanga Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaView further author information
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Xuan Zenga Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaView further author information
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Hao Wua Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaView further author information
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Hong Liua Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. ChinaCorrespondence[email protected] [email protected]
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Hong-liang Yaoa Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P.R. China;b Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Drug Synthesis and Evaluation Center, Guangdong Institute of Applied Biological Resources, Guangzhou, P.R. ChinaCorrespondence[email protected] [email protected]
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Pages 1077-1086 | Received 12 May 2020, Accepted 03 Sep 2020, Published online: 14 Sep 2020

Figures & data

Figure 1. Effects of NXT on whole blood viscosity (WBV) in the rat blood stasis model.

Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05 compared with the model group.

Figure 1. Effects of NXT on whole blood viscosity (WBV) in the rat blood stasis model.Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05 compared with the model group.

Figure 2. Effects of NXT on plasma viscosity (PV) in the rat blood stasis model.

Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05 compared with the model group.

Figure 2. Effects of NXT on plasma viscosity (PV) in the rat blood stasis model.Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05 compared with the model group.

Figure 3. Effects of NXT on prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) in the rat blood stasis model.

Note: Data are presented as means ± SD (n = 7). *P < 0.05, **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 3. Effects of NXT on prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) in the rat blood stasis model.Note: Data are presented as means ± SD (n = 7). *P < 0.05, **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 4. Effects of NXT on alanine transaminase (ALT) and aspartate transaminase (AST) in the rat blood stasis model.

Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 4. Effects of NXT on alanine transaminase (ALT) and aspartate transaminase (AST) in the rat blood stasis model.Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 5. Effects of NXT on total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and malonaldehyde (MDA) in the rat blood stasis model.

Note: Data are presented as means ± SD (n = 7). *P < 0.05, **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 5. Effects of NXT on total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and malonaldehyde (MDA) in the rat blood stasis model.Note: Data are presented as means ± SD (n = 7). *P < 0.05, **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 6. Effects of NXT on interleukin-1β (IL-1β) and interleukin-6 (IL-6) in the rat blood stasis model.

Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 6. Effects of NXT on interleukin-1β (IL-1β) and interleukin-6 (IL-6) in the rat blood stasis model.Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, #P < 0.05, ##P < 0.01 compared with the model group.

Figure 7. Effects of NXT on platelet activating factor (PAF) in the rat blood stasis model.

Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, ##P < 0.01 compared with the model group.

Figure 7. Effects of NXT on platelet activating factor (PAF) in the rat blood stasis model.Note: Data are presented as means ± SD (n = 7). **P < 0.01 compared with the normal group, ##P < 0.01 compared with the model group.

Data availability statement

The data that support the findings of this study are available from the corresponding author, H.L., upon reasonable request.

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