Preoperative ultrasound assessment of myometrial invasion in endometrial cancer and prediction of surgical stage

Figures & data

Table 1. Demographic characteristics for 180 patients diagnosed with endometrial cancer by D&C or hysteroscopy.

Parameters	Number (n = 180) or median (range)	Percentage (%)
Age at time of diagnosis, years	65 (41–85)
Age at menopause (years)	51 (43–57)
Postmenopausal	164	91.11
Premenopausal	16	8.89
Endocrine-metabolic disorders – inc. Obesity, Diabetes, Arterial Hypertension	91	50.56
Arterial Hypertension and other cardiovascular disease	51	28.33
Other diseases	21	11.67
Without diseases	17	9.44
Parity
≥1	154	85.56
0	26	14.44
Clinical symptoms
Abnormal bleeding	135	75
Vaginal discharge with abnormal bleeding	15	8.33
Vaginal discharge	10	5.56
Without	20	11.11

Data are presented as median (range), n (%).

Table 2. Histological findings at hysterectomy in 180 patients diagnosed with endometrial cancer by D&C or hysteroscopy and type of surgery.

Parameters	Number of patients (n)	Percentage (%)
Carcinoma in situ	12	6.66
Tumor stage (FIGO)
IA	85	47.22
IB	45	25
II	30	16.68
IIIA	6	3.33
IV	2	1.11
Histological type and grade
Endometrioid or mucinous	144/168	85.71
Grade 1	39/168	23.22
Grade 2	102/168	60.71
Grade 3	27/168	16.07
Non-endometrioid	24/168	14.29
Type of surgery
Open surgery	61/180	33.88
Laparoscopic method	28/180	15.56
Robot-assisted method	91/180	50.56

FIGO, International Federation of Gynecology and Obstetrics.

Table 3. Preoperative ultrasound detected cases compared with postoperative results on the degree of myometrial invasion—less and more than 50%.

		Preoperative ultrasound assessment n = 161	Postoperative results n = 144	Statistics
				χ2	p	Phi	p(Phi)
Myometrial invasion	Under 50%	55.9%	56.3%	0.04	0.951	0.004	0.951
	Over 50%	44.1%	43.8%

Table 4. Postoperative results on tumor differentiation and the degree of myometrial invasion/distribution of cases with tumor differentiation versus myometrial invasion.

		Myometrial invasion		Statistics
		Under 50% n = 81	Over 50% n = 63	χ2	p	V	p(V)
Differentiation	G1 – highly differentiated carcinoma	35.8%	4.8%	19.81	0.05*	0.37	0.05*
	G2 – moderately differentiated carcinoma	49.4%	71.4%
	G3 – low-grade carcinoma	14.8%	23.8%

* Statistically significant difference.