Diagnostic value of hybrid perfusion SPECT/CT and CTPA for detection of pulmonary embolism

Figures & data

Figure 1. CTPA (A) and P-SPECT/CT (B) of Case 1. (A) CTPA of pulmonary artery, main, lobar and segmental branches without visible defects of filling. In the area of left lung lingula parenchyma consolidation and filling defect in the level of subsegmental branches. Small pleural effusion on the left. (B) Perfusion SPECT/CT in the left lung showing perfusion defect in lung lingula with parenchyma consolidation. Small pleural effusion. In the right lung hypoperfusion defects in small branches in lower lobe.

Figure 2. CTPA (A) and P-SPECT (B) of Case 2. (A) CTPA with no filling defects in pulmonary artery, its main, lobar and segmental branches, which are of normal size. (B) Perfusion SPECT/CT showing both side hypoperfusion in the subsegmental level of pulmonary artery.

Table 1. Crosstable of imaging methods.

Imaging methods	Modality	Positive	Negative	Total
P-SPECT/CT	PE	107	6	113
	NO PE	22	11	33
	Total	129	17	146
CTPA	PE	46	1	47
	NO PE	33	9	42
	Total	79	10	89

Table 2. Diagnostic value of the imaging methods.

Modality	Imaging methods
	P-SPECT/CT	CTPA
Sensitivity (%)	82.9	58.2
Specificity (%)	64.7	90
PPV (%)	94.7	97.9
NPV (%)	33.3	21.4
Accuracy (%)	80.8	61.8
Nondiagnostic rate (%)	2.7	0

Data availability statement

The data that support the findings of this study are available from the corresponding author [Sevda Naydenska], upon reasonable request.