Figures & data
Table 1. Primer sequences used for real-time quantitative reverse transcriptase polymerase chain reaction (qRT-PCR).
Table 2. Biochemical serum parameters from control and treated rats.
Figure 1. Real-time RT-PCR analysis of IL-6 and TNF-α mRNA in liver (A, B) and kidney (C, D) from control and treated rats. Values are presented as ratio fold change of mRNA to control group. Data are mean ± SEM. *p < 0.05, **p < 0.01 versus CTRL; ≠ p < 0.05, ≠ ≠ p < 0.01 versus DM. CTRL: control group, DM: Alloxan-induced diabetic rats, UCMS: unpredictable chronic mild stress group, DM + UCMS: combined group.
![Figure 1. Real-time RT-PCR analysis of IL-6 and TNF-α mRNA in liver (A, B) and kidney (C, D) from control and treated rats. Values are presented as ratio fold change of mRNA to control group. Data are mean ± SEM. *p < 0.05, **p < 0.01 versus CTRL; ≠ p < 0.05, ≠ ≠ p < 0.01 versus DM. CTRL: control group, DM: Alloxan-induced diabetic rats, UCMS: unpredictable chronic mild stress group, DM + UCMS: combined group.](/cms/asset/ea2477d9-673f-46f3-8b49-9f26f7c65cfd/tbeq_a_2182137_f0001_b.jpg)
Figure 2. Levels of proinflammatory cytokines, IL-6 and TNF-α in liver (A, B) and kidney (C, D) determined by ELISA. Data are mean ± SEM. *p < 0.05, **p < 0.01 versus CTRL; ≠ ≠ p < 0.01 versus DM; # p < 0.05, ## p < 0.01 versus UCMS. CTRL: control group, DM: Alloxan-induced diabetic rats, UCMS: unpredictable chronic mild stress group, DM + UCMS: combined group.
![Figure 2. Levels of proinflammatory cytokines, IL-6 and TNF-α in liver (A, B) and kidney (C, D) determined by ELISA. Data are mean ± SEM. *p < 0.05, **p < 0.01 versus CTRL; ≠ ≠ p < 0.01 versus DM; # p < 0.05, ## p < 0.01 versus UCMS. CTRL: control group, DM: Alloxan-induced diabetic rats, UCMS: unpredictable chronic mild stress group, DM + UCMS: combined group.](/cms/asset/2032dea6-bdba-476b-8d1f-2629832fcf06/tbeq_a_2182137_f0002_b.jpg)
Figure 3. Antioxidant enzymes activities, SOD (A), CAT (B) and MDA level (C) in liver and kidney from control and treated rats. Data are mean ± SEM. **p < 0.01 versus CTRL; ≠ ≠ p < 0.01 versus DM; # p < 0.05, ## p < 0.01 versus UCMS. CTRL: control group, DM: Alloxan-induced diabetic rats, UCMS: unpredictable chronic mild stress group, DM + UCMS: combined group.
![Figure 3. Antioxidant enzymes activities, SOD (A), CAT (B) and MDA level (C) in liver and kidney from control and treated rats. Data are mean ± SEM. **p < 0.01 versus CTRL; ≠ ≠ p < 0.01 versus DM; # p < 0.05, ## p < 0.01 versus UCMS. CTRL: control group, DM: Alloxan-induced diabetic rats, UCMS: unpredictable chronic mild stress group, DM + UCMS: combined group.](/cms/asset/4bbb8ead-7c79-4e61-a592-ec6a2916d943/tbeq_a_2182137_f0003_b.jpg)
Data availability statement
The data that support the findings of this study are available at from the corresponding author, upon reasonable request.