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Biotechnology & Biotechnological Equipment Volume 38, 2024 - Issue 1
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Review Article

Applicability of biosensor technologies in the detection of Coxiella burnetii infection in clinical samples

Petia Genova-Kaloua Department of Virology, National Center of Infectious and Parasitic Diseases, Sofia, BulgariaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3820-3658View further author information
ORCID Icon,
Georgi Dyankovb Department of Composite and Nanostructured Optical Materials, Institute of Optical Materials and Technologies ‘Acad. Jordan Malinowski’, Bulgarian Academy of Sciences, Sofia, BulgariaView further author information
,
Stefka Krumovaa Department of Virology, National Center of Infectious and Parasitic Diseases, Sofia, BulgariaORCID Iconhttps://orcid.org/0000-0001-6941-0989View further author information
ORCID Icon,
Konstantin Simeonovc Department of Epizootiology and Infectious Diseases of Animals, National Diagnostic and Research Veterinary Medical Institute ‘Prof. Dr. G. Pavlov’, Bulgarian Food Safety Agency, Sofia, BulgariaView further author information
,
Trifon Valkovd Department of Infectious Diseases, Medical University of Sofi[a, Prof. Ivan Kirov Hospital, Sofia, BulgariaView further author information
,
Magdalena Baymakovae Department of Infectious Diseases, Military Medical Academy, Sofia, BulgariaView further author information
,
Ilia Tsachevf Department of Microbiology, Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, BulgariaView further author information
&
Pierre-Edouard Fournierg Unité des Rickettsies, Faculté de Médecine, IHU-Méditerranée Infection, Marseille, FranceView further author information
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Article: 2350163 | Received 11 Feb 2024, Accepted 26 Apr 2024, Published online: 07 May 2024

Figures & data

Figure 1. The spectral displacement due to the bimolecular interaction ‘structural C. burnetii protein – specific anti-C. burnetii antibody’ registered against the functionalized biochip; black curve: the SPR signal of functionalized biochip; red curve: the SPR signal after antigen binding.

Figure 1. The spectral displacement due to the bimolecular interaction ‘structural C. burnetii protein – specific anti-C. burnetii antibody’ registered against the functionalized biochip; black curve: the SPR signal of functionalized biochip; red curve: the SPR signal after antigen binding.

Figure 2. Application of serological and molecular-biology methods for detection of acute Q fever.

Figure 2. Application of serological and molecular-biology methods for detection of acute Q fever.

Data availability statement

The data that support the findings from this study are available from the corresponding author [PGK] upon reasonable request.

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