The effects of percutaneous transluminal coronary intervention on biomarkers of oxidative stress in the erythrocytes of elderly male patients

Figures & data

Table 1. Inclusion and exclusion criteria for participation in the study.

Groups of patients	Criteria for inclusion	Criteria for exclusion
PTCA group	- Gender: male - SAP - Indications for PTCA in accordance with guidelines - Informed consent for PTCA - Informed consent for participation in the study	- Acute/chronic inflammation - Suspicion/diagnosis of acute coronary syndrome - Short duration between EC and PTCA (<3 weeks) - Ineffective PTCA - Local treatment complications - Addiction to alcohol/tobacco - Diabetes mellitus or other conditions of known free radical etiology
EC group	- Gender: male - Indications for planned EC in accordance with guidelines - Informed consent for EC - Informed consent for participation in the study	- Acute/chronic inflammation - The need to perform PTCA concurrently - Local treatment complications - Addiction to alcohol/tobacco - Diabetes mellitus or other conditions of known free radical etiology

Figure 1. Effect of PTCA on the (a) MDA and (b) reduced GSH concentrations in the erythrocytes of male patients with SAP compared with the effect of diagnostic EC on the erythrocytes of male subjects (control group). Data are presented as the means ± S.E.M. *p < 0.001, before the procedure versus 14 days after the procedure, ^#p < 0.001, SAP patients versus control subjects.

Figure 2. Effect of PTCA on the activities of antioxidant enzymes in the erythrocytes of male patients with SAP compared with the effect of diagnostic EC on the erythrocytes of male subjects (control group): (a) Cu–Zn SOD-1, (b) CAT, (c) cellular GSH-Px. Data are presented as the means ± S.E.M. *p < 0.05, before the procedure versus 14 days after the procedure, ^#p < 0.05, SAP patients versus control subjects.

Table 2. Clinical characteristics of the patients included in the study.

Parameter	PTCA group (n = 23)	EC group (n = 18)	p value
Age, Yrs (mean ± S.E.M.)	63.8 ± 2.22	60.4 ± 3.54	0.30
Body weight, kg (mean ± S.E.M.)	85.4 ± 3.74	87.6 ± 2.87	0.48
Height, M (mean ± S.E.M.)	1.73 ± 0.017	1.74 ± 0.010	0.98
Body mass index, kg/m^2 (mean ± S.E.M.)	28.5 ± 0.95	29.0 ± 0.88	0.98
High cholesterol, n (%)	20 (83.3)	11 (57.9)	0.02
High blood pressure, n (%)	18 (75.0)	14 (73.7)	0.99
Previous myocardial infarction, n (%)	9 (37.5)	4 (21.1)	0.11
Previous PTCA, n (%)	8 (33.3)	3 (15.8)	0.13