Figure 1. Small-molecule antagonists of the PD-1 pathway.
Figure 2. PD-1/PD-L1 inhibitors synthesized by BMS.
Figure 3. False positive PD-1/PD-L1 inhibitors.
Figure 4. Peptidomimetic inhibitors of the PD-1/PD-L1 interaction with oxa- and thiadiazole core moieties.
Figure 5. a) Hydrolysis-resistant D-peptide antagonist to target the PD-1/PD-L1 b) Macrocyclic peptidic inhibitor c) Peptide antagonist of PD-L1 (10) along with its sequence similarities to PD-1.
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