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Neurocase
Behavior, Cognition and Neuroscience
Volume 19, 2013 - Issue 6
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Clozapine as a potential treatment for refractory impulsive, compulsive, and punding behaviors in Parkinson’s disease

A. HardwickDepartment of Neurology, Center for Movement Disorders & Neurorestoration, Gainesville, FL, USA
,
H. WardDepartment of Neurology, Center for Movement Disorders & Neurorestoration, Gainesville, FL, USA
,
A. HassanDepartment of Neurology, Center for Movement Disorders & Neurorestoration, Gainesville, FL, USA
,
J. RomrellDepartment of Neurology, Center for Movement Disorders & Neurorestoration, Gainesville, FL, USA
&
M. S. OkunDepartment of Neurology, Center for Movement Disorders & Neurorestoration, Gainesville, FL, USACorrespondence[email protected]
Pages 587-591 | Received 19 Jan 2012, Accepted 03 Jul 2012, Published online: 30 Aug 2012
 
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Abstract

There have been emerging cases of medication refractory obsessions, impulsivity, compulsivity, and/or punding in Parkinson’s disease. These cases have proven difficult to treat, even for the experienced clinician. We report several medication refractory cases with a positive response to treatment with clozapine.

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