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Behavior, Cognition and Neuroscience
Volume 24, 2018 - Issue 4
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Articles

Verbal adynamia in parkinsonian syndromes: behavioral correlates and neuroanatomical substrate

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Pages 204-212 | Received 10 Sep 2017, Accepted 10 Sep 2018, Published online: 06 Oct 2018

Figures & data

Table 1. Summary of group demographic, clinical, and background neuropsychological data.

Table 2. Summary of participant group performance on verbal adynamia battery.

Figure 1. Scatter plots showing individual raw scores for all participant groups on tasks assessing verbal adynamia (sentence completion, sentence generation, letter fluency; see text for details) and on control tasks (Delis-Kaplan executive function system design fluency, Graded naming test, Sentence Production Program for Aphasia expressive grammar subtest). Note changes of vertical axis between tests. HC, healthy controls; PDD, patients with Parkinson’s disease dementia; PSP/CBS, patients with progressive supranuclear palsy/corticobasal syndrome.

Figure 1. Scatter plots showing individual raw scores for all participant groups on tasks assessing verbal adynamia (sentence completion, sentence generation, letter fluency; see text for details) and on control tasks (Delis-Kaplan executive function system design fluency, Graded naming test, Sentence Production Program for Aphasia expressive grammar subtest). Note changes of vertical axis between tests. HC, healthy controls; PDD, patients with Parkinson’s disease dementia; PSP/CBS, patients with progressive supranuclear palsy/corticobasal syndrome.

Table 3. Neuroanatomical associations of patient performance on verbal adynamia tests.

Figure 2. Statistical parametric maps (SPMs) showing regional gray matter atrophy significantly associated with task performance for sentence completion using an unconstrained word (left) or a phrase (right) in the combined patient cohort. SPMs are thresholded at p < 0.05 after small volume correction for multiple voxel-wise comparisons in pre-specified small anatomical volumes of interest and displayed on sagittal sections of the left hemisphere from a group mean T1-weighted MR brain template image in Montreal Neurological Institute standard space.

Figure 2. Statistical parametric maps (SPMs) showing regional gray matter atrophy significantly associated with task performance for sentence completion using an unconstrained word (left) or a phrase (right) in the combined patient cohort. SPMs are thresholded at p < 0.05 after small volume correction for multiple voxel-wise comparisons in pre-specified small anatomical volumes of interest and displayed on sagittal sections of the left hemisphere from a group mean T1-weighted MR brain template image in Montreal Neurological Institute standard space.
Supplemental material

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