The relationship between erectile dysfunction severity, mean platelet volume and vitamin D levels

Figures & data

Figure 1. Comparison of vitamin D and MPV levels between mild and severe ED groups.

Table 1. Comparison of mild and severe ED group.

	Mild ED		Severe ED
	Mean ± SD	Median	Mean ± SD	Median	p
Age (years)	39.80 ± 8.51	40.00	42.63 ± 8.37	43.00	.127^a
Partner age (years)	38.44 ± 7.87	39.00	39.63 ± 7.84	40.00	.475^a
Height (cm)	174.98 ± 5.56	175.00	172.39 ± 7.87	172.00	.074^b
Weight (kg)	83.34 ± 11.26	82.00	82.90 ± 13.56	80.00	.827^b
BMI (kg/m²)	27.23 ± 3.62	26.78	27.89 ± 4.14	27.89	.315^b
Total testosterone (ng/ml)	4.12 ± 1.03	3.98	4.05 ± 0.98	3.89	.537^b
25(OH)D (ng/ml)	18.79 ± 6.00	18.82	14.03 ± 7.15	13.18	.000^b
IIEF score	24.44 ± 4.03	25.00	12.08 ± 3.52	13.00	.000^b
MPV (fl)	10.07 ± 0.85	9.90	10.79 ± 1.03	10.80	.001^b

^a Mann–Whitney U-test.

^b t-test.

Bold values indicate that 25(OH)D levels, IIEF scores and MPV levels were statistically significant between groups.

Figure 2. (a) Serum vitamin D levels were positively correlated with IIEF scores. (b) Serum MPV levels were negatively correlated with IIEF scores. (c) Serum MPV levels were negatively correlated with vitamin D levels.

Figure 3. The activities of MPV > 10 fl and 25(OH)D of <15 ng/ml, respectively [area under the curve 0.764 (0.662–0.865)] was considered significant.

Table 2. ROC curve analysis for Vitamin D and MPV levels.

	Area under curve (95% CI)	p	Sensitivity (%)	Specificity (%)
Vitamin D < 15	0.723 (0.615–0.831)	.000	71.4	73.2
MPV > 10	0.699 (0.587–0.811)	.001	83.7	56.1
MPV > 10 + Vitamin D < 15	0.764 (0.662–0.865)	.000	67.3	85.4

Bold values indicate that sensitivity and specificity were statistically significant.