25-Hydroxy cholecalciferol, anti-Müllerian hormone, and thyroid profiles among infertile men

Figures & data

Figure 1. 25-Hydroxy cholecalciferol and anti-Müllerian hormone levels (A), and thyroid profiles (B) and reproductive hormones (C) among men with azoospermia, men with oligoasthenoteratozoospermia, and the controls.

Table 1. Comparison between serum levels of the measured hormones (Vitamin D3, AMH, gonadotropins, prolactin, free testosterone, TSH, FT3, and FT4) among the studied groups.

Variables	Group A (N = 105)	Group B (N = 96)	Group C (N = 100)	p-Value
25-hydroxy cholecalciferol (ng/mL) mean ± SD	19.87 ± 4.58	11.85 ± 2.16	40.88 ± 4.53	.000*
AMH (ng/mL) mean ± SD	4.76 ± 2.61	5.01 ± 2.26	5.08 ± 1.54	.968
FSH(mIU/mL) mean ± SD	4.14 ± 0.36	10.05 ± 2.93	3.8 ± 0.53	.000*
LH (mIU/mL) mean ± SD	4.39 ± 1.84	5.85 ± 1.44	3.74 ± 0.4	.476
PRL(ng/mL) mean ± SD	14.42 ± 1.06	13.82 ± 2.68	13.22 ± 1.32	.519
Free testesterone (pg/mL) mean ± SD	48.15 ± 7.45	14.45 ± 0.54	52.94 ± 1.04	.000*
TSH(µIU/mL) mean ± SD	2.16 ± 0.64	4.17 ± 0.38	2.26 ± 0.86	.001*
FT3(pg/mL) mean ± SD	3.23 ± 0.49	3.59 ± 0.28	3.34 ± 0.57	.530
FT4(ng/dL) mean ± SD	1.59 ± 0.4	1.22 ± 0.16	1.72 ± 0.25	.082

Group A: oligoasthenoteratozoospermia patients; Group B: azoospermic patients; Group C: controls; AMH: anti-mullerian hormone; FSH: follicle stimulating hormone; LH: leuteinizing hormone; PRL: prolactin; TSH: thyroid stimulating hormone; FT3: free triiodothyronine; FT4: free tetraiodothyronine; SD: standard deviation. ANOVA was used.

*Statistically significant at p ≤ .05.

Figure 2. Negative correlation between thyroid-stimulating hormone and luteinizing hormone, positive correlation between anti-Müllerian hormone and luteinizing hormone among oligoasthenoteratozoospermia patients (A,B); positive correlation between luteinizing hormone and 25-hydroxyl cholecalciferol among men with azoospermia (C).