Levels of TNF-α, IL-6, IL-17, IL-37 cytokines in patients with active vitiligo

Figures & data

Table 1. Demographic and clinical characteristics of the study sample.

Characteristics	Patient group	Control group
N	48	18
Age (years), mean ± SD	30.48 ± 9.86	28.27 ± 9.66
Female, n (%)	25 (52.1)	7 (38.9)
Male, n (%)	23 (47.9)	11 (61.1)
Disease duration (months), mean ± SD	115.54 ± 95.46	–

Table 2. Descriptive statistics and between-group t-test outcomes.

Outcomes	Patient group (n = 48)	Control group (n = 18)	t-test outcomes
	Mean ± SD	Mean ± SD	t	p	Cohen’s d [95% CI]
IL-37 (ng/ml)	17.09 ± 17.17	6.25 ± 5.30	3.90	.000	.85 [.50–1.64]
IL-6 (ng/ml)	46.40 ± 63.09	13.80 ± 12.99	3.39	.001	.72 [.37–1.50]
IL-17 (ng/ml)	63.43 ± 90.33	30.60 ± 37.98	2.08	.042	.47 [.02–1.12]
TNF-α (ng/ml)	160.56 ± 163.10	46.52 ± 25.85	4.69	.000	.98 [.71–1.88]

Figure 1. Bar graphs demonstrating the serum IL-6 levels of the patient and control groups.

Figure 2. Bar graphs demonstrating the serum IL-37 levels of the patient and control groups.

Figure 3. Bar graphs demonstrating the serum TNF-α levels of the patient and control groups.

Figure 4. Bar graphs demonstrating the serum IL-17 levels of the patient and control groups.