Is erectile dysfunction an early clinical symptom of chronic kidney disease?

Figures & data

Table 1. Age distribution, mean creatinine, GFR values, and median IIEF scores according to CKD stage in the study group.

CKD Stage	Number of patients (n = 639)	Age (years)	Creatinine (mg/dL)	GFR (mL/min)	IIEF
0	444	58.69 ± 8.15	0.84 ± 0.12	112.10 ± 27.47	47 ± 31
1	167	68.62 ± 7.7	1.0 ± 0.16	74.68 ± 12.62	31 ± 42
2	28	75.18 ± 7.67	1.23 ± 0.43	47.99 ± 9.71	15 ± 34

Table 2. Distribution of CKD frequency in ED groups.

Erectile dysfunction	CKD stage
	0	1	2	p Value
None	86 (81.9)	18 (17.1)	1 (1.0)
Mild	83 (78.3)	21 (19.8)	2 (1.9)	.000*** (χ^2=41.172) CC = 0.245
Mild–moderate	79 (76.7)	21 (20.4)	3 (2.9)
Moderate	80 (72.1)	26 (23.4)	5 (4.5)
Severe	115 (54.0)	81 (38.0)	17 (8.0)

χ²: likelihood ratio chi-square; CC: contingency coefficient.

*** Statistically significant (p<.001).

Table 3. Comparison with one-way ANCOVA of IIEF scores taking age as covariate in CKD and control groups.

Variables	CKD	N	Mean	SD	Minimum	Maximum	p Value
Age	No	443	58.83	8.00	40.00	82.00	.000***
	Yes	195	69.56	8.01	44.00	92.00
IIEF	No	443	16.79	8.53	1.00	30.00	.000**
	Yes	195	12.17	8.99	1.00	29.00

** Statistically significant (one-way ANCOVA, p<.001).

***Statistically significant (Student’s t-test, p<.001).