Figures & data
Figure 1. Undercarboxylated osteocalcin levels in the studied group. Box plot of undercarboxylated osteocalcin among healthy eugonadal, subclinical hypognadism and late onset hypogonadism groups. Each box indicates the 25th and 75th percentiles, the median is represented by the horizontal line within the box, the extreme measured values are indicated by whiskers. Dots and stars represent the outliers.
![Figure 1. Undercarboxylated osteocalcin levels in the studied group. Box plot of undercarboxylated osteocalcin among healthy eugonadal, subclinical hypognadism and late onset hypogonadism groups. Each box indicates the 25th and 75th percentiles, the median is represented by the horizontal line within the box, the extreme measured values are indicated by whiskers. Dots and stars represent the outliers.](/cms/asset/b86367a1-76ab-4b14-a5e2-31591977f90c/itam_a_2049744_f0001_c.jpg)
Table 1. Clinical, laboratory, and endothelial function parameters of the groups studied.
Table 2. Correlation between reproductive hormone levels, hypothalamo-pituitary testicular axis regulatory factors (LH/T, LH × T, and E/T ratio) and undercarboxylated osteocalcin on the one hand and studied cardiovascular risk factors and endothelial function parameters on the other hand, in all study subjects.
Table 3. Correlation between reproductive hormone levels, hypothalamo-pituitary testicular axis regulatory factors (LH/T, LH × T, and E/T ratio) and undercarboxylated osteocalcin on the one hand and studied cardiovascular risk factors and endothelial function parameters on the other hand in the subclinical hypogonadism group.
Table 4. Correlation between reproductive hormone levels, hypothalamo-pituitary testicular axis regulatory factors (LH/T, LH × T, and E/T ratio) and undercarboxylated osteocalcin on the one hand and studied cardiovascular risk factors and endothelial function parameters on the other hand in the late-onset hypogonadism group.
Table 5. Multiple linear regression analysis to assess the role of reproductive hormones, studied hypothalamo-pituitary regulatory factors and undercarboxylated osteocalcin as independent predictors of endothelial function parameters in all study participants.
Table 6. Multiple linear regression analysis to assess role of reproductive hormones, studied hypothalamo-pituitary regulatory factors and undercarboxylated osteocalcin as independent predictors of endothelial function parameters in the late-onset hypogonadism group.
Data availability statement
The datasets generated and analyzed during the present study are not publicly accessible due to concerns of participant confidentiality but are offered by the corresponding author on realistic request.