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Cardiovascular

Healthcare resource utilization and expenditures among newly-diagnosed elderly non-valvular atrial fibrillation patients initiating oral anticoagulants

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Pages 1338-1350 | Received 14 Jun 2019, Accepted 20 Sep 2019, Published online: 12 Oct 2019

Figures & data

Figure 1. Study design. Abbreviation. AF, atrial fibrillation. The identification period in the figure is shown as an example of case selection for the dabigatran vs. warfarin comparison.

Figure 1. Study design. Abbreviation. AF, atrial fibrillation. The identification period in the figure is shown as an example of case selection for the dabigatran vs. warfarin comparison.

Table 1. Sample size before and after propensity score matching.

Figure 2. Patient attrition. Abbreviations. AF, atrial fibrillation; NOAC, novel oral anticoagulant; NVAF, non-valvular atrial fibrillation; OAC, oral anticoagulant.

Figure 2. Patient attrition. Abbreviations. AF, atrial fibrillation; NOAC, novel oral anticoagulant; NVAF, non-valvular atrial fibrillation; OAC, oral anticoagulant.

Table 2. Baseline demographics and clinical characteristics (before propensity score matching).

Table 3. Baseline demographic, clinical characteristics, costs & HRU of newly-diagnosed and newly-treated NVAF patients after PSM.

Figure 3. Adjusted all-cause HRU among patients with NVAF prescribed warfarin, rivaroxaban or apixaban vs. dabigatran. Abbreviations. ER, emergency room; PPPM, per patient per month. Covariates adjusted included age, sex, race, US region, CHA2Ds2-VASc, and HAS-BLED score.

Figure 3. Adjusted all-cause HRU among patients with NVAF prescribed warfarin, rivaroxaban or apixaban vs. dabigatran. Abbreviations. ER, emergency room; PPPM, per patient per month. Covariates adjusted included age, sex, race, US region, CHA2Ds2-VASc, and HAS-BLED score.

Figure 4. Adjusted all-cause healthcare costs among patients with NVAF prescribed warfarin, rivaroxaban or apixaban vs. dabigatran. Abbreviations. ER, emergency room; PPPM, per patient per month. Covariates adjusted included age, sex, race, US region, CHA2Ds2-VASc, and HAS-BLED score.

Figure 4. Adjusted all-cause healthcare costs among patients with NVAF prescribed warfarin, rivaroxaban or apixaban vs. dabigatran. Abbreviations. ER, emergency room; PPPM, per patient per month. Covariates adjusted included age, sex, race, US region, CHA2Ds2-VASc, and HAS-BLED score.
Supplemental material

Supplemental data for this article is available online at https://doi.org/10.1080/13696998.2019.1672698.

Download MS Excel (72.8 KB)

Data availability

The raw insurance claims data used for this study originate from Medicare data, which are available from the Centers for Medicare and Medicaid through ResDAC (https://www.resdac.org/).

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