Estimating the public economic consequences of cardiovascular disease-attributable events and evolocumab treatment in Australia

Figures & data

Table 1. Annual public benefit transfers for fiscal states Active and Disabled.

	Fiscal state
	Active		Disabled
Age (years)	Average taxable welfare benefit	Average non-taxable welfare benefit	Average taxable welfare benefit	Average non-taxable welfare benefit
40–44	$1,112	$596	$-	$21,497
45–49	$719	$714	$-	$21,984
50–54	$596	$552	$-	$21,955
55–59	$773	$1,198	$-	$21,863
60–64	$973	$1,248	$253	$21,047
65–69	$7,103	$1,481	$7,385	$19,398
70–74	$7,103^a	$1,481^a	$8,578	$22,485
75–79	$7,103^a	$1,481^a	$8,901	$20,332
80 and above	$7,103^a	$1,481^a	$6,594	$20,822

^aAligned with government initiatives to reduce state pensions for retirees, we applied the average welfare benefit reported for those age 65–69 provided to 48% of the population applied to other ages as this reflects future projections for cohorts considered in the model.

Table 2. Average annual net income taxes paid (direct taxes) and Medicare levy for active and disabled persons.

	Fiscal state
	Active		Disabled
Age (years)	Average annual net income tax	Average annual Medicare levy	Average annual net income tax	Average annual Medicare levy
40–44	$15,923	$1,375	$10	$-
45–49	$15,096	$1,292	$20	$1
50–54	$14,302	$1,245	$96	$1
55–59	$11,594	$1,045	$2	$-
60–64	$7,894	$743	$14	$3
65–69	$4,124	$375	$-	$-
70–74	$1,623	$144	$-	$-
75–79	$1,084	$85	$424	$44
80 and above	$1,108	$90	$-	$-

Figure 1. Univariate sensitivity analysis of key parameters on fiscal benefit cost ratio for persons aged 50-years-old in Australia.

Table 3. Incremental change in fiscal parameters based on treatment starting age (evolocumab – current treatment practice).

Category	Fiscal parameter	Incremental change – age 40	Incremental change – age 50	Incremental change – age 60
Government spending	Total medical	$41,352	$40,488	$38,384
	Medical (1)	$4,341	$4,344	$4,325
	Evolocumab (2)	$45,694	$44,832	$42,709
	Transfers (3)	$3,483	$2,495	$4,619
Societal earnings	Indirect costs	$23,256	$11,601	$2,354
Government revenue	Tax (4)	$15,716	$9,810	$4,217
Life years gained		0.7	0.7	0.6
fBCR (1 + 3 + 4)/(2)		0.52	0.37	0.31