https://orcid.org/0000-0002-9173-3335
Figures & data
Figure 1. Flow diagram showing the study population identified in the PPRN. aInfants born <28 weeks GA are the primary focus of the analyses reported in this article. bGiven the restrictive treatment policy of infants born at ≤24 weeks GA in the Netherlands, the study cohort only included pregnancies from 24 weeks GA onwards. Abbreviations. GA, gestational age; PPRN, PHARMO Perinatal Research Network.
Figure 2. Percentage of infants with additional comorbidities at birth by birth period.
Table 1. Selected infant and maternal characteristics by morbidity status during birth hospitalization of infants in the PHARMO Perinatal Research Network born EP (<28 weeks GA) from 1999 to 2015.
Table 2. Adjusted model predicting long LOS of birth hospitalizationa among EP infants (<28 weeks GA) in the PHARMO Perinatal Research Network born from 1999 to 2015.
Figure 3. Frequency of hospital readmissions at 1- and 2-years CA after birth among EP (<28 weeks gestational age) infants in the PHARMO Perinatal Research Network. (a) Infants with a birth record from 1999 to 2015 by pulmonary morbidity cohort. aWithin the time periods of outcome assessment (note: cohort sizes can therefore be larger than those presented at birth). (b) Frequency of hospital readmissions at 1- and 2-years CA after birth among EP infants in the PHARMO Perinatal Research Network with a birth record from 1999 to 2005, 2006 to 2009, and 2010 to 2015. Abbreviations. BPD, bronchopulmonary dysplasia; CA, corrected age; CLD, chronic lung disease; EP, extremely preterm; IQR, interquartile range; LOS, length of stay; PY, person-year.
Figure 4. Mean costs of birth hospitalization for EP infants (<28 weeks gestational age). (a) By pulmonary morbidity; (b) by birth period. Abbreviations. BPD, bronchopulmonary dysplasia; CLD, chronic lung disease; EP, extremely preterm; SD, standard deviation.
Figure 5. Costs of health care resource utilization among EP infants (<28 weeks gestational age). (a) By pulmonary morbidity; (b) by birth period. Costs are for infants with data available on birth hospitalization. Abbreviations. BPD, bronchopulmonary dysplasia; CA, corrected age; CLD, chronic lung disease; EP, extremely preterm; PY, person-year.
