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Oncology

Clinical and economic burden of HPV-related cancers in the US veteran population

ORCID Icon, , , &
Pages 299-308 | Received 01 Nov 2021, Accepted 10 Feb 2022, Published online: 03 Mar 2022

Figures & data

Table 1. Baseline patient characteristics for matched patients with and without HPV-related cancers.

Figure 1. Annual prevalence and incidence rates for HPV-related cancers. Abbreviation. FY, fiscal year.

Figure 1. Annual prevalence and incidence rates for HPV-related cancers. Abbreviation. FY, fiscal year.

Figure 2. Adjusted annual health care costs for matched patients with and without HPV-related cancers, per patient per year. Abbreviations: Cases, cancer patients; Controls, patients without cancer, p-value was significant (<0.001) across outcomes. Control patients had no diagnosis claim for any cancer throughout the study period and were assigned an arbitrary index date within the identification period. After cohort assignment, case and control patients were matched based on age, race, cancer group, and sex for non-sex specific cancers (oropharyngeal and anal cancer). The overall case-to-control matching ratio was 1:4. Due to limited sample size, patients with vulvar or vaginal cancer were combined into a single vulvovaginal cancer cohort.

Figure 2. Adjusted annual health care costs for matched patients with and without HPV-related cancers, per patient per year. Abbreviations: Cases, cancer patients; Controls, patients without cancer, p-value was significant (<0.001) across outcomes. Control patients had no diagnosis claim for any cancer throughout the study period and were assigned an arbitrary index date within the identification period. After cohort assignment, case and control patients were matched based on age, race, cancer group, and sex for non-sex specific cancers (oropharyngeal and anal cancer). The overall case-to-control matching ratio was 1:4. Due to limited sample size, patients with vulvar or vaginal cancer were combined into a single vulvovaginal cancer cohort.

Table 2. Adjusted annual health care utilization results for matched patients with and without HPV-related cancers.

Supplemental material

Supplemental Material

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