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Genetic Disease

Healthcare resource utilization and costs in individuals with Huntington’s disease by disease stage in a US population

ORCID Icon, , , , ORCID Icon, , & show all
Pages 722-729 | Received 06 Dec 2021, Accepted 10 May 2022, Published online: 03 Jun 2022

Figures & data

Figure 1. HD attrition flowchart. HD, Huntington’s disease.

Figure 1. HD attrition flowchart. HD, Huntington’s disease.

Table 1. Participant characteristics by HD stage at baseline.

Table 2. Any all-cause HRU within 6-months post-index by baseline HD stage.

Figure 2. Mean all-cause HRU PPPM by post-index HD stage. The non-parametric Friedman test was used for comparing the three HD stages. Individuals can contribute person-time and HRU to each category based on stages in follow-up. Outpatient visits, inpatient visits, ER visits, and pharmacy visits are mutually exclusive. HD-related pharmacy claims are a subset of pharmacy claims. Radiology and PT/OT procedures are subsets of inpatient and outpatient visits. ER, emergency room; HD, Huntington’s disease; HRU, healthcare resource utilization; PPPM, per patient per month; PT, physical therapy; OT, occupational therapy.

Figure 2. Mean all-cause HRU PPPM by post-index HD stage. The non-parametric Friedman test was used for comparing the three HD stages. Individuals can contribute person-time and HRU to each category based on stages in follow-up. Outpatient visits, inpatient visits, ER visits, and pharmacy visits are mutually exclusive. HD-related pharmacy claims are a subset of pharmacy claims. Radiology and PT/OT procedures are subsets of inpatient and outpatient visits. ER, emergency room; HD, Huntington’s disease; HRU, healthcare resource utilization; PPPM, per patient per month; PT, physical therapy; OT, occupational therapy.

Figure 3. Mean all-cause healthcare costs PPPM (2018 USD) by post-index HD stage. Individuals can contribute person-time and HRU to each category based on stages in follow-up. Outpatient costs, inpatient costs, and pharmacy costs are mutually exclusive. HD-related pharmacy claims are a subset of pharmacy costs. Long-term care/nursing and skilled nursing facility are subsets of inpatient and outpatient costs. HD, Huntington’s disease; PPPM, per patient per month; SNF, skilled nursing facility.

Figure 3. Mean all-cause healthcare costs PPPM (2018 USD) by post-index HD stage. Individuals can contribute person-time and HRU to each category based on stages in follow-up. Outpatient costs, inpatient costs, and pharmacy costs are mutually exclusive. HD-related pharmacy claims are a subset of pharmacy costs. Long-term care/nursing and skilled nursing facility are subsets of inpatient and outpatient costs. HD, Huntington’s disease; PPPM, per patient per month; SNF, skilled nursing facility.
Supplemental material

Supplemental Material

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