Comparing Mattis Dementia Rating Scale – initiation / perseveration subset and frontal assessment battery in stroke associated with small vessel disease

Abstract

Forty-two controls and 32 patients with stroke associated with small vessel disease (SSVD) were administered the Mattis Dementia Rating Scale Initiation / Perseveration subset (MDRS I/P) and Frontal Assessment Battery (FAB). Both tests showed comparably good ability in Receiver Operating Characteristics curves analysis (AUC_MDRS I/P = 0.887; AUC _FAB = 0.854, p = .833) in discriminating between controls and patients and correctly classified over 78% of subjects. Verbal fluency and motor programming contributed most to the discriminating power in the two tests. The MDRS I/P and FAB are useful in discriminating between controls and SSVD patients in a hospital setting.

Acknowledgments

This study was supported by the Neurology research fund of Division of Neurology, Department of Medicine and Therapeutics, Chinese University of Hong Kong.