Chemerin levels in metabolic syndrome: a promising biomarker

Figures & data

Table 1. Chemerin levels in metabolic syndrome.

Authors/Country	Mets criteria	Chemerin (ug/L)	Pertinent comments
1. Stejskal et al. 2008 Czech Republic	+ Males and females n = 59 with MetS	285 ± 80.1 vs. 228.9 ± 41.1 (p < .01)	Correlations with glucose, BP, TG, HDL-C but not with HOMA-IR and WC CRP not reported
2. Dong et al. 2011 China	+ Males and females n = 46 with MetS	111.6 ± 37.3 vs. 95.1 ± 29.7 p = .01	Also showed chemerin higher in MetS with CAD Correlations with BMI, BP, TG, CRP but not with HDL-C and HOMA-IR
3. Jialal et al. 2013 USA	+ Males and females n = 45 with MetS	366 ± 64 vs. 271 ± 53 p < .0001	Also showed increased SAT secreted chemerin Correlations with TG, BP, HDL-C, CRP, HOMA-IR
4. Wang et al. 2013 China	+ Males and females n = 30 with MetS	97.6 ± 6.5 vs. 70.3 ± 7.0 p < .05	Significant correlations with WC, BP, BG, HBAIC, Insulin and HDL-C
5. Aksan, et al. 2014 Turkey	+ Males and females n = 41 with MetS	115.7 ± 15.2 vs. 90.4 ± 11.4 p < .17	Also showed chemerin higher in MetS with CAD Correlations with BMI, BP, TG, BG, HDL-C. Both CRP and HOMA-IR not reported. 54% smokers

BP: blood pressure; TG: triglycerides; HDL-C: high density lipoprotein-cholesterol; BMI: body mass index; WC: waist circumference; BG: blood glucose; CRP: C-reactive protein; HBA1c: glycated haemoglobin; HOMA-IR: homeostasis model of assessment of insulin resistance.

Stejskal, D., et al., 2008. Chemerin is an independent marker of the metabolic syndrome in a Caucasian population – a pilot study. Biomedical papers, 152 (2), 217–221.

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Dong, B., Ji, W., and Zhang, Y., 2011. Elevated serum chemerin levels are associated with the presence of coronary artery disease in patients with metabolic syndrome. Internal Medicine, 50 (10), 1093–1097.

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Jialal, I., et al., 2013. Increased chemerin and decreased omentin-1 in both adipose tissue and plasma in nascent metabolic syndrome. The journal of clinical endocrinology and metabolism, 98 (3), E514–517.

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Wang, D., et al., 2013. Plasma Chemerin level in metabolic syndrome. Genetics and molecular research, 12 (4), 5986–5991.

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Aksan, G., et al., 2014. Association of serum chemerin levels with severity of coronary artery disease in patients with metabolic syndrome. International journal of clinical and experimental medicine, 7 (12), 5461–5468.

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Data availability statement

The data cited by the author in this Editorial are published in various manuscripts as referenced. However, the data from the author’s studies are available on request from the author, Professor I. Jialal and not in the public domain to respect confidentiality and protect participant privacy.