Figures & data
Figure 1. Patient flow with symptom severity and impact on daily activities during follow-up. Patients (absolute numbers are shown) are divided per follow-up moment with respect to symptom resolution and those still symptomatic to severity of symptoms. Total numbers of patients in the study: 266 at week 2, 264 at week 4, 257 at week 8, and 248 at week 12.
![Figure 1. Patient flow with symptom severity and impact on daily activities during follow-up. Patients (absolute numbers are shown) are divided per follow-up moment with respect to symptom resolution and those still symptomatic to severity of symptoms. Total numbers of patients in the study: 266 at week 2, 264 at week 4, 257 at week 8, and 248 at week 12.](/cms/asset/7c1f8823-ed38-4ce7-b6c1-40cba2bf320a/igen_a_2154074_f0001_b.jpg)
Table 1. Characteristics of COVID-19 outpatients at inclusion.
Figure 2. Frequency and severity of self-reported symptoms in COVID-19 outpatients over 12 weeks after a positive SARS-CoV-2 test. Absolute numbers of patients reporting each individual symptom are shown, with severity distribution.
![Figure 2. Frequency and severity of self-reported symptoms in COVID-19 outpatients over 12 weeks after a positive SARS-CoV-2 test. Absolute numbers of patients reporting each individual symptom are shown, with severity distribution.](/cms/asset/67d10365-5a23-4435-a24c-a5c3d525da23/igen_a_2154074_f0002_c.jpg)
Figure 3. Correlation of COVID-19-related symptoms between week 2 and week 12. Univariate correlation between presence and severity of symptoms at week 2 (column) and week 12 (row). Darker tones correspond to stronger correlations. Empty cells indicate no patients with that particular symptom combination at week 2 and 12.
![Figure 3. Correlation of COVID-19-related symptoms between week 2 and week 12. Univariate correlation between presence and severity of symptoms at week 2 (column) and week 12 (row). Darker tones correspond to stronger correlations. Empty cells indicate no patients with that particular symptom combination at week 2 and 12.](/cms/asset/0905b92d-d32c-4e4f-a477-137acbbedf6c/igen_a_2154074_f0003_c.jpg)
Table 2. Impact on daily activities reported by outpatients with lingering COVID-19-related symptoms.
Figure 4. Correlations between COVID-19-related symptoms at week 2 and their impact on daily life variables at week 12. Univariate correlations between presence and severity of symptoms week 2 (column) and impact on daily life at week 12 (row). Darker tones correspond to stronger correlation.
![Figure 4. Correlations between COVID-19-related symptoms at week 2 and their impact on daily life variables at week 12. Univariate correlations between presence and severity of symptoms week 2 (column) and impact on daily life at week 12 (row). Darker tones correspond to stronger correlation.](/cms/asset/497ed4ea-3275-44d1-bb2f-16242dbbc018/igen_a_2154074_f0004_c.jpg)
Figure 5. Cox regression for time to return to usual health for obese patients compared to non-obese. Graph shows the hazard for obese patients (red) and non-obese patients (blue). Outcomes were adjusted for age, sex, sore throat and gastrointestinal manifestations (variables included in the final model, p-value = 0.007). Y-axis starts at 0.3 to better visualise the difference between lines. The X-axis shows number of weeks.
![Figure 5. Cox regression for time to return to usual health for obese patients compared to non-obese. Graph shows the hazard for obese patients (red) and non-obese patients (blue). Outcomes were adjusted for age, sex, sore throat and gastrointestinal manifestations (variables included in the final model, p-value = 0.007). Y-axis starts at 0.3 to better visualise the difference between lines. The X-axis shows number of weeks.](/cms/asset/41a9a642-ee1d-4aa3-b791-dab335ddc56b/igen_a_2154074_f0005_c.jpg)