Yinzhihuang oral liquid in the treatment of neonatal jaundice: a meta-analysis

Figures & data

Figure 1. Study selection.

Table 1. The characteristics of the included studies.

Author	Year published	Cased T/C	Sex male/female
Liang (2014)	2014	60/60	68/52
Lin and Cui (2011)	2011	64/64	76/68
Wang et al. (2010)	2010	90/90	100/80
Gao (2011)	2011	38/38	/
Shao and Li (2013)	2013	80/80	/
Chen (2013)	2013	77/83	95/65
Zhao et al. (2014)	2014	41/40	48/33
Liu et al. (2013)	2013	50/50	52/48
Xv (2011)	2011	60/60	69/51
Yu et al. (2013)	2013	102/98	109/91
Xiang (2014)	2014	123/123	137/109
Zhang (2014)	2014	62/61	65/58
Mu et al. (2015)	2015	43/43	46/40
Chen and Yang (2013)	2013	39/30	39/30
Yang and Ren (2011)	2011	24/25	28/21
Jiang (2011)	2011	150/150	174/126
Qiu and Wang (2014)	2014	60/60	/
Zhu (2014)	2014	40/40	46/34
Guo (2013)	2013	98/98	136/60

T: trial group; C: control group; /: no report.

Table 2. Intervention and outcome measures of the included studies.

	Intervention
Author (year)	Trial group	Control group	Outcomemeasures
Liang (2014)	Phototherapy + YOL	Phototherapy	Efficacy
Lin and Cui (2011)	RT + YOL	RT	Efficacy
Wang et al (2010)	RT + YOL	RT	Efficacy
Gao (2011)	RT + YOL	RT	Efficacy
Shao and Li (2013)	Phototherapy + YOL	Phototherapy	Efficacy
Chen (2013)	RT + YOL	RT	Efficacy, TCB
Zhao et al. (2014)	RT + YOL	RT	Efficacy
Liu et al. (2013)	RT + YOL	RT	TSB
Xv (2011)	RT + YOL	RT	Efficacy
Yu et al. (2013)	RT + YOL	RT	Efficacy, TSB
Xiang (2014)	RT + YOL	RT	Efficacy
Zhang (2014)	RT + YOL	RT	Efficacy
Mu et al. (2015)	Phototherapy + YOL	Phototherapy	Efficacy
Chen and Yang (2013)	RT + YOL	RT	TSB
Yang and Ren (2011)	RT + YOL	RT	Efficacy
Jiang (2011)	RT + YOL	RT	Efficacy, TCB
Qiu and Wang (2014)	Phototherapy + YOL	Phototherapy	Efficacy
Zhu (2014)	RT + YOL	RT	Efficacy
Guo (2013)	RT + YOL	RT	Efficacy

YOL: Yingzhihuang oral liquid; RT: Routine treatment; TSB: total serum bilirubin; TCB: transcutaneous bilirubin.

Figure 2. Methodological quality assessment of the risk of bias for each included study.

Figure 3. Effective rates of comparison between treatment and the control group.

Figure 4. Meta-analysis of the bilirubin levels of Yingzhihuang oral liquid group and the control group during treating neonatal jaundice on third day.

Figure 5. Meta-analysis of the bilirubin levels of Yingzhihuang oral liquid group and the control group during treating neonatal jaundice on fifth day.

Figure 6. Meta-analysis of the subsiding time of jaundice of Yingzhihuang oral liquid and the control group.

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