Figures & data
Figure 1. Photomicrographs are representative of cross sections from six rats stained with hematoxylin and eosin. (A) showing pancreas of normal rat with normal pancreatic tissue including islets of Langerhans, pancreatic acini and ducts, (B) showing pancreas of diabetic rat with islet destruction, reduction in size and lymphocytic infiltration, (C) representing pancreas of Momordica charantia pretreated diabetic rat showing mild islets destruction, (D) showing pancreas of diabetic rat treated with Momordica charantia with moderate islet destruction (H&E 250×).
Figure 2. Effect of oral administration of 50% Momordica charantia (MC) fruit juice (10 mL/kg) on serum cholesterol (A), triglycerides (B) and serum HDL-C (C), in pretreated and treated diabetic rats. (n = 6), *p < 0.05 (significantly different from normal group); #p < 0.05 (significantly different from diabetic group) by one-way ANOVA and Bonferroni post hoc test.
Figure 3. Effect of oral administration of 50% Momordica charantia (MC) fruit juice (10 mL/kg) on serum total antioxidant capacity (TOAC) (A), pancreatic reduced glutathione (GSH) (B) and pancreatic MDA (C), in pretreated and treated diabetic rats. (n = 6), *p < 0.05 (significantly different from normal group); #p < 0.05 (significantly different from diabetic group) by one-way ANOVA and Bonferroni post hoc test.
Table 1. Effect of oral administration of 50% Momordicacharantia (MC)fruit juice (10 ml/kg) on serum glucose, insulin, insulin resistance index, β-cell function percent and serum fructosamine level, in diabetic rats.
Table 2a. Effect of 0.5% Momordica charantia (MC) fruit juice (0.02 ml) and STZ on glucose uptake of diaphragms isolated from normal rats in absence and in presence of insulin.
Table 2b. Effect of 0.5% Momordica charantia (MC) fruit juice (0.02 ml) on glucose uptake of diaphragms isolated from diabetic rats in absence and in presence of insulin.