Further insight into the bioactivity of the freshwater sponge Ochridaspongia rotunda

Figures & data

Table 1. The Ames test: Ochridaspongia rotunda acetone extract.

	Revertant colonies (CFU/plate)^a
	TA98		TA100		TA102
Extract	− S9	+ S9	− S9	+ S9	− S9	+ S9
Control	16 ± 4	20 ± 2	113 ± 11	105 ± 13	250 ± 21	276 ± 26
DMSO (50 μL/plate)	19 ± 5	18 ± 3	103 ± 5	120 ± 16	298 ± 19	286 ± 14
0.106 mg/plate	16 ± 2	33 ± 6	119 ± 6	102 ± 9	340 ± 18	355 ± 5
0.265 mg/plate	22 ± 3	28 ± 4	165 ± 13	133 ± 11	306 ± 10	290 ± 9
0.531 mg/plate	20 ± 2	24 ± 5	103 ± 14	90 ± 3	308 ± 15	261 ± 20
1.328 mg/plate	24 ± 6	27 ± 2	108 ± 2	140 ± 10	281 ± 7	296 ± 16
4-NQO (1 μg/plate)	–	–	856 ± 87*	811 ± 48*	1917 ± 195*	2159 ± 67*
EtBr (50 μg/plate)	23 ± 6	648 ± 68*	–	–	–	–

^a Mean values ± SD of three experiments.

* Significantly different (p < 0.05).