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Research Article

Effect of piplartine and cinnamides on Leishmania amazonensis, Plasmodium falciparum and on peritoneal cells of Swiss mice

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Pages 1601-1607 | Received 07 Aug 2016, Accepted 23 Mar 2017, Published online: 17 Apr 2017

Figures & data

Figure 1. Percentage of MTT reduction by cultures of L. amazonensis (A) and peritoneal cells of Swiss mice (B) after 6 h of incubation, and inhibition of growth of P. falciparum after 48 (C1) or 72 (C2) h of incubation.

Figure 1. Percentage of MTT reduction by cultures of L. amazonensis (A) and peritoneal cells of Swiss mice (B) after 6 h of incubation, and inhibition of growth of P. falciparum after 48 (C1) or 72 (C2) h of incubation.

Table 1. Chemical structure of piplartine (1) and cinnamides (2–5), and concentrations able to inhibit 50% of the cells (IC50), L. amazonensis, P. falciparum and peritoneal cells of Swiss mice.