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Research Article

Sika pilose antler type I collagen promotes BMSC differentiation via the ERK1/2 and p38-MAPK signal pathways

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Pages 2196-2204 | Received 10 Feb 2017, Accepted 11 Oct 2017, Published online: 08 Nov 2017

Figures & data

Figure 1. Assessment of SPC-I on cell proliferation of BMSC via the CCK-8 assay.

Figure 1. Assessment of SPC-I on cell proliferation of BMSC via the CCK-8 assay.

Figure 2. The effects and evaluation of SPC-I on BMSC differentiation into osteoblasts.

Figure 2. The effects and evaluation of SPC-I on BMSC differentiation into osteoblasts.

Figure 3. The effect of SPC-I on the gene expression of osteogenesis markers and gene and osteogenesis transcription regulation gene (with U0126).

Figure 3. The effect of SPC-I on the gene expression of osteogenesis markers and gene and osteogenesis transcription regulation gene (with U0126).

Figure 4. The effect of SPC-I on the gene expression of ERK1/2 during BMSC differentiation into osteoblasts.

Figure 4. The effect of SPC-I on the gene expression of ERK1/2 during BMSC differentiation into osteoblasts.

Figure 5. The effect of SPC-I on the protein expression of ERK1/2 and p-ERK1/2 (without and with U0126).

Figure 5. The effect of SPC-I on the protein expression of ERK1/2 and p-ERK1/2 (without and with U0126).

Figure 6. The effect of SPC-I on the expression of BMP2 and p38-MAPK.

Figure 6. The effect of SPC-I on the expression of BMP2 and p38-MAPK.