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Research Article

The α-amylase and α-glucosidase inhibitory activities of the dichloromethane extracts and constituents of Ferulago bracteata roots

, , , , , , & show all
Pages 18-24 | Received 07 Mar 2017, Accepted 05 Dec 2017, Published online: 12 Dec 2017

Figures & data

Table 1. 1 H NMR (400 MHz) and 13 C NMR (100 MHz) data of 1 in CDCl3.

Figure 1. Chemical structures of compounds 1–12.

Figure 1. Chemical structures of compounds 1–12.

Figure 2. Significant HMBC (→) correlations of compound 1.

Figure 2. Significant HMBC (→) correlations of compound 1.

Figure 3. α-Glucosidase inhibition (%) of extracts and fractions of roots from Ferulago bracteata at different concentrations. The different extracts and fractions were compared with acarbose and p < 0.05 (p = 0.0004).

Figure 3. α-Glucosidase inhibition (%) of extracts and fractions of roots from Ferulago bracteata at different concentrations. The different extracts and fractions were compared with acarbose and p < 0.05 (p = 0.0004).

Figure 4. α-Glucosidase inhibition effects (%) of compounds 1–10. The isolated coumarins were compared with acarbose and p <0.05 (p = 0.0437).

Figure 4. α-Glucosidase inhibition effects (%) of compounds 1–10. The isolated coumarins were compared with acarbose and p <0.05 (p = 0.0437).

Table 2. α-Glucosidase inhibitory activities of extracts, fractions and compounds 1–10.