Bioactive metabolites from the leaves of Withania adpressa

Widad Ben BakrimDepartment of Biology, Faculty of Sciences Semlalia, Laboratory of Biotechnology, Protection and Valorisation of Plant Resources (URAC35 association Unit), Cadi Ayyad University, Marrakech, Morocco; View further author information

Laila El BouzidiDepartment of Biology, Faculty of Sciences Semlalia, Laboratory of Biotechnology, Protection and Valorisation of Plant Resources (URAC35 association Unit), Cadi Ayyad University, Marrakech, Morocco; View further author information

Jean-Marc NuzillardInstitut de Chimie Moléculaire de Reims, UMR CNRS 7312, SFR Cap-Santé FED 4231, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims, France;

http://orcid.org/0000-0002-5120-2556 View further author information

Sylvian CrettonSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva 4, SwitzerlandView further author information

Noémie SarauxSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva 4, SwitzerlandView further author information

Aymeric MonteillierSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva 4, SwitzerlandView further author information

Philippe ChristenSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva 4, Switzerland

http://orcid.org/0000-0003-4713-0323 View further author information

Muriel CuendetSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva 4, SwitzerlandCorrespondence[email protected]

http://orcid.org/0000-0002-1523-1907 View further author information

Khalid BekkoucheDepartment of Biology, Faculty of Sciences Semlalia, Laboratory of Biotechnology, Protection and Valorisation of Plant Resources (URAC35 association Unit), Cadi Ayyad University, Marrakech, Morocco;

http://orcid.org/0000-0002-6864-5003 View further author information

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Bioactive metabolites from the leaves of Withania adpressa

Table 1. ¹H-(500 MHz) and ¹³C-(125 MHz) NMR data of compound 5 (CDCl₃).

Table 2. NF-ĸB inhibition mediated by the isolated compounds (1-5)Table Footnote^a.

Table 3. Antiproliferative activity of the isolated compounds (1–5) in MM-CSCs and RPMI 8226 cellsTable Footnote^a.

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Bioactive metabolites from the leaves of Withania adpressa

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Table 1. 1H-(500 MHz) and 13C-(125 MHz) NMR data of compound 5 (CDCl3).

Table 2. NF-ĸB inhibition mediated by the isolated compounds (1-5)Table Footnotea.

Table 3. Antiproliferative activity of the isolated compounds (1–5) in MM-CSCs and RPMI 8226 cellsTable Footnotea.

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Table 1. ¹H-(500 MHz) and ¹³C-(125 MHz) NMR data of compound 5 (CDCl₃).

Table 2. NF-ĸB inhibition mediated by the isolated compounds (1-5)Table Footnote^a.

Table 3. Antiproliferative activity of the isolated compounds (1–5) in MM-CSCs and RPMI 8226 cellsTable Footnote^a.