Figures & data
Figure 2. Routine blood parameters. (A) WBC relative change in male mice; (B) RBC relative change in male mice; (C) WBC relative change in female mice; (D) RBC relative change in female mice; (E) HCT relative change in female mice; (F) HGB relative change in female mice. Control: control group; Model: model group (CTX group); Low: low dose group; Middle: middle dose group; High: high dose group. Note: The Y-axis of (D–F) is displayed in −%. *p < 0.05; **p < 0.01.
![Figure 2. Routine blood parameters. (A) WBC relative change in male mice; (B) RBC relative change in male mice; (C) WBC relative change in female mice; (D) RBC relative change in female mice; (E) HCT relative change in female mice; (F) HGB relative change in female mice. Control: control group; Model: model group (CTX group); Low: low dose group; Middle: middle dose group; High: high dose group. Note: The Y-axis of (D–F) is displayed in −%. *p < 0.05; **p < 0.01.](/cms/asset/eacf9139-772a-433f-8e98-433dc91742ea/iphb_a_1941133_f0002_b.jpg)
Figure 3. Histopathology of the spleen. (A) Splenic index; (B) Spleen of the control group; (C) Spleen of the model group; (D) Spleen of the low-dose group; (E) Spleen of the middle dose group; (F) Spleen of the high-dose group. *p < 0.05; **p < 0.01.
![Figure 3. Histopathology of the spleen. (A) Splenic index; (B) Spleen of the control group; (C) Spleen of the model group; (D) Spleen of the low-dose group; (E) Spleen of the middle dose group; (F) Spleen of the high-dose group. *p < 0.05; **p < 0.01.](/cms/asset/28c98dfd-7c4b-4ec6-b2fd-47de43fffb62/iphb_a_1941133_f0003_c.jpg)
Figure 4. Histopathological observations of femoral bone marrow. (A) Femoral bone marrow of the control group; (B) Femoral bone marrow of the model group; (C) Femoral bone marrow of the low-dose group; (D) Femoral bone marrow of the middle dose group; (E) Femoral bone marrow of the high-dose group.
![Figure 4. Histopathological observations of femoral bone marrow. (A) Femoral bone marrow of the control group; (B) Femoral bone marrow of the model group; (C) Femoral bone marrow of the low-dose group; (D) Femoral bone marrow of the middle dose group; (E) Femoral bone marrow of the high-dose group.](/cms/asset/c0c96987-a473-42eb-a42e-0481e5cb0da2/iphb_a_1941133_f0004_c.jpg)
Table 1. Top 10 key nodes of natural medicines and actin target.
Table 2. Top 15 in the SXF PPI network ranked by degree.