The association of total antioxidant capacity with sex hormones

Figures & data

Table I.  Total antioxidant activity and sex hormones in males and females groups of subject

	Females		Males
	Menopausal (n=19)	Premenopausal (n=32)	Normal T (n=10)	Lower T (n=36)
Age, year	41±4	40±4	39±4	38±5.6
TAC, mEquiv/L	0.91±0.25	1.54±0.29*	1.87±0.22	1.16±0.31†
BMI, kg/m2	24.6±4.8	23.5±5.5	23.9±3.8	24.9±2.9
Estradiol, pmol/L	54.31±1.21	151.16±52.48*	ND	ND
(N Range)	(0.0–110.1)	(113.4–205.52)
T, nmol/L	ND	ND	23.14±4.64	5.72±1.66†
(N Range)	(0.52–34.7)	(0.52–34.7)

Data are reported as means±SD for each group. BMI; body mass index, N; normal, ND; not detected, TAC: total antioxidant capacity,_T; testosterone

*p<0.001 vs. menopausal female group.

† p<0.001 vs. normal testosterone male group.

Figure 1. Total antioxidant capacity (TAC) of male and female subjects. FM = female menopausal, FPM = female pre menopausal, MLT = male with lower testosterone, MN = male with normal testosterone. Values are means±SD for each group. *p<0.001

Figure 2a. The correlation between total antioxidant capacity (TAC) and total testosterone

Figure 2b. The correlation between total antioxidant capacity (TAC) and estradiol

Table II.  Bivariate and multivariate regression analyses for predicting for TAC in female and male subjects

	Bivariate analysis		Multivariate analysis
	r	p	β	p
For female
Age	−0.2800	.047	0.018	0.814
Body mass index	−0.395	0.004	−0.156	0.044
Estradiol	0.685	<0.001	0.818	<0.001
For men
Age	0.413	0.004	0.262	0.030
Body mass index	0.381	0.020	0.381	0.020
Testosterone	0.807	<0.001	0.560	<0.001

TAC; total antioxidant capacity