Changes in glycaemic control are related to the systolic function in type 1 diabetes mellitus

Figures & data

Table I.  Changes in glycaemic control and left ventricular function during follow-up.

	Baseline	Follow-up
Insulin dose (IE/day)	46±15	39±12*
HbA1c (%)	8.6±1.4	7.6±1.1*
Peak systolic velocity (cm/s)	7.3±2	7.5±3
Systolic strain rate (s^−1)	−1.58±0.30	−1.80±0.4*
Heart rate (bpm)	75±10	78±8
Systolic blood pressure (mmHg)	121±6	119±7
Diastolic blood pressure (mmHg)	75±5	77±5
e/a ratio	1.3±0.1	1.4±0.2
E-decelleration time (ms)	186±20	196±18
E’- velocity (cm/s)	12.5±1.3	12.7±1.6
E’/A’ ratio	1.8±0.5	1.9±0.6
Left ventricular mass (g)	150±27	147±23

*p < 0.05.

Figure 1.  A) Inter-individual changes in left ventricular strain rate during insulin pump therapy (−1.58±0.30 s-1 to −1.80±0.4 s-1, p < 0.01). B) Correlation between changes in strain rate and changes in HbA_1c during follow-up.

Figure 2.  Correlation between the age at baseline and the changes in systolic strain rate.