Figures & data
Table 1. Baseline characteristics for overall and Japanese patient populations in Studies RA-BEAM and RA-BEGIN.
Figure 1. Correlations between PtGA and PhGA and clinical measures at baseline, Week 12, and Week 24 for overall and Japanese patient populations in Studies RA-BEAM (a) and RA-BEGIN (b). All variables were significantly correlated with PtGA and PhGA (p < .05) except for:RA-BEAM: • SJC28 and PtGA at baseline in the Japanese patient population • MCS and PtGA at Week 24 in the Japanese patient population • MCS and PhGA at baseline, Week 12, and Week 24 in the Japanese patient population • QIDS-SR16 and PtGA at Week 24 in the Japanese patient population • QIDS-SR16 and PhGA at baseline and Week 24 in the Japanese patient populationRA-BEGIN: • hsCRP/SJC28/TCJ28 and PtGA at baseline in the Japanese patient population • ESR and PtGA at baseline, Week 12, and Week 24 in the Japanese patient population • ESR/SJC28/TJC28 and PhGA at baseline in the Japanese patient population • MCS and PhGA at baseline in the Japanese patient populationEQ-5D VAS: European Quality of Life-5 Dimensions VAS; ESR: erythrocyte sedimentation rate; FACIT-F: Functional Assessment of Chronic Illness Therapy-Fatigue Scale; HAQ-DI: Health Assessment Questionnaire-Disability Index; hsCRP: high-sensitivity C-reactive protein; MCS: Mental Component Score; PCS: Physical Component Score; PhGA: Physician’s Global Assessment of Disease Activity; PtGA: Patient’s Global Assessment of Disease Activity; QIDS-SR16: Quick Inventory of Depressive Symptomatology-Self-Rated (16 items); SJC28: swollen joint count in 28 joints; TJC28: tender joint count in 28 joints; VAS: visual analog scale.
Figure 2. Contribution of variables to PtGA and PhGA at baseline, Week 12, and Week 24 for Japanese and overall patient populations in Studies RA-BEAM (a) and RA-BEGIN (b). EQ-5D VAS: European Quality of Life-5 Dimensions VAS; ESR: erythrocyte sedimentation rate; FACIT-F: Functional Assessment of Chronic Illness Therapy-Fatigue Scale; HAQ-DI: Health Assessment Questionnaire-Disability Index; hsCRP: high-sensitivity C-reactive protein; MCS: Mental Component Score; PCS: Physical Component Score; PhGA: Physician’s Global Assessment of Disease Activity; PtGA: Patient’s Global Assessment of Disease Activity; RA: rheumatoid arthritis; SJC28: swollen joint count in 28 joints; TJC28: tender joint count in 28 joints; VAS: visual analog scale.
