Psychiatric disorders in women and men up to five years after undergoing assisted reproductive technology treatment – a prospective cohort study

Figures & data

Table 1. Sociodemographic and medical characteristics of the study population.

	Women (n = 278)	Men (n = 183)
Age, years (mean ± SD)	38.3 ± 3.9	39.7 ± 4.7
Body Mass Index, kg/m^2	24.9 ± 4.5	–
Employment status
Employed	217 (78%)	170 (92.9%)
Student	15 (5.4%)	1 (0.5%)
Parental leave	28 (10.1%)	4 (2.2%)
Unemployed	9 (3.3%)	3 (1.6%)
Sick-leave	7 (2.5%)	5 (2.7%)
Living with same partner	258 (92.8%)	181 (98.9%)
Living with children	255 (91.7%)	171 (93.4%)
ART
Terminated treatment	217 (78%)	150 (82.4%)
Not decided whether to continue treatment	42 (15.1%)	19 (7.1%)
Want or plan to continue treatment	19 (6.8%)	13 (10.4%)
Sick-leave during ART	40 (14.4%)	3 (1.6%)
Counsellor/psychologist at follow-up	18 (6.5%)	6 (3.3%)

Table 2. Prevalence of psychiatric disorders detected by PRIME-MD at five-year follow-up.

	Women (n = 278)	Men (n =183)
Any psychiatric diagnosis at baseline	76 (27.3%)	11 (6.0%)
Any psychiatric diagnosis at follow-up^a	32 (11.5%)	10 (5.5%)
Any depressive disorder at follow-up	26 (9.4%)	8 (4.4%)
Major depressive disorder	16 (5.7%)	6 (3.3%)
Dysthymia	2 (0.7%)	4 (2.2%)
Partial remission of major depressive disorder	5 (1.8%)	1 (0.5%)
Minor depressive disorder	11 (4%)	2 (1.1%)
Any anxiety disorder at follow-up	15 (5.4%)	5 (2.7%)
Anxiety NOS^b	8 (2.9%)	1 (0.5%)
Generalized anxiety disorder	5 (1.8%)	3 (1.6%)
Panic disorder	3 (1.1%)	3 (1.6%)

^a Study participants can have one or more psychiatric diagnoses within any mood and/or any anxiety disorders.

^b NOS: not otherwise specified.

Table 3. Any psychiatric diagnosis among women and men in logistic regression.

	Women (n = 278)				Men (n = 183)
	Psychiatric diagnosis				Psychiatric diagnosis
	Yes = 32	No = 246	Adjustedoddsratio (OR)	95.0%confidenceinterval	Yes = 10	No = 173	Adjustedoddsratio (OR)	95.0%confidenceinterval
Previous psychiatric diagnosis^a
Yes	16 (50.0)	58 (23.6)	3.64*	1.63–8.10	3 (30.0)	8 (4.6)	4.69*	0.79–27.83
No	16 (50.0)	188 (76.4)	–	–	7 (70.0)	165 (95.4)	–	–

* p < 0.05.

^a Missing items = 2.