How does one choose the appropriate pharmacotherapy for pediatric patients with functional dyspepsia?

Figures & data

Table 1. Available Medications for Treatment of Functional Dyspepsia in Children.

Medication	Dose
Anti-acid therapy
Omeprazole	1–2 mg/kg/day (maximum 40 daily)
Ranitidine	4–8 mg/kg/day divided, twice daily
Drugs enhancing gastric accommodation
Buspirone	5 mg at bedtime or twice daily if needed
Neuromodulators
Mirtazapine	7.5–15 mg at bedtime
Amitriptyline	10–25 mg at bedtime
Prokinetic agents
Erythromycin	1–3 mg/kg/dose before meals
Metoclopramide	0.1–0.2 mg/kg/dose before meals
Miscellaneous
Cyproheptadine	0.25 mg/kg/day

Figure 1. Therapeutic algorithm for functional dyspepsia in children.