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Special Report

The potential for rapid antigen testing for mucormycosis in the context of COVID-19

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Pages 161-167 | Received 19 Apr 2023, Accepted 04 Jul 2023, Published online: 07 Jul 2023

Figures & data

Figure 1. Clinical manifestations of infection by Mucorales fungi. Following inhalation of air-borne sporangiospores released from sporangia (blue structures), rapidly progressive angio-invasive infections of the paranasal sinuses by invasive hyphae can lead to rhino-orbital-cerebral mucormycosis (ROCM). ROCM is categorized as: localized sinus, localized orbital, localized cerebral, sino-orbital, sino-cerebral, rhino-cerebral and generalized ROCM. Inhalation of spores into the lungs can result in localized and deep extension (infections involve the lungs, chest wall, heart, artery or aorta) pulmonary mucormycosis, while necrotizing cutaneous mucormycosis caused by traumatic implant of infective propagules in the skin can lead to disseminated disease of the lungs, liver, spleen, heart, and other organs following hematogenous spread of Mucorales fungi from the sites of infection. Image courtesy of Shutterstock.

Figure 1. Clinical manifestations of infection by Mucorales fungi. Following inhalation of air-borne sporangiospores released from sporangia (blue structures), rapidly progressive angio-invasive infections of the paranasal sinuses by invasive hyphae can lead to rhino-orbital-cerebral mucormycosis (ROCM). ROCM is categorized as: localized sinus, localized orbital, localized cerebral, sino-orbital, sino-cerebral, rhino-cerebral and generalized ROCM. Inhalation of spores into the lungs can result in localized and deep extension (infections involve the lungs, chest wall, heart, artery or aorta) pulmonary mucormycosis, while necrotizing cutaneous mucormycosis caused by traumatic implant of infective propagules in the skin can lead to disseminated disease of the lungs, liver, spleen, heart, and other organs following hematogenous spread of Mucorales fungi from the sites of infection. Image courtesy of Shutterstock.