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Expert Review of Neurotherapeutics Volume 20, 2020 - Issue 12
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Original Research

From QAAPAPLE 1 to QAAPAPLE 2: how do we move from one algorithm to another one with Long Acting Antipsychotics (LAIs)

Emmanuel Stipa College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates;b Centre Hospitalier Universitaire de Montreal (CHUM), Institute Universitaireen Santé Mentale de Montréal, Université de Montreal, Montreal, CanadaCorrespondence[email protected]
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Sylvain Grignonc Department of Psychiatry, University of Sherbrooke, Sherbrooke, QC, Canada;d Department of Psychiatry, University of Laval, Quebec, QC, CanadaView further author information
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Marc André Royd Department of Psychiatry, University of Laval, Quebec, QC, Canada;e Department of Psychiatry, McGill University, Montreal, QC, CanadaView further author information
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David Bloome Department of Psychiatry, McGill University, Montreal, QC, CanadaView further author information
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Ossama Osmanf Department of Psychiatry and Behavioral Sciences, McGovern Medical School, the University of Texas Health Science Center, Texas, USAView further author information
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Leena Amiria College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab EmiratesView further author information
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Karim Abdel Aziza College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab EmiratesView further author information
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Syed Fahad Javaida College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab EmiratesORCID Iconhttps://orcid.org/0000-0001-6467-8150View further author information
ORCID Icon &
Danilo Arnonea College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates;g Kings’ College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Psychological Medicine, Centre for Affective Disorders, London, UKView further author information
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Pages 1325-1332 | Received 22 Apr 2020, Accepted 18 Sep 2020, Published online: 18 Oct 2020

Figures & data

Figure 1. Upgrading QAAPAPLE 1 to QAAPAPLE 2

Québec Algorithme Antipsychotique à Action Prolongée means Algorithm from Quebec for Long Acting Antipsychotic. Quebec is a Province of Canada.
Figure 1. Upgrading QAAPAPLE 1 to QAAPAPLE 2

Figure 2. QAAPAPLE 1 and QAAPAPLE 2. LAI: Long Acting Injectable antipsychotic. (a) Short interval between injection; (b) long Interval between injection

NMS: Neuroleptic Malignant Syndrome. MS: Multiple sclerosis. The QAAPABLE 2 is an updated version of QAAPAPLE 1. Diverse versions of the algorithm have been presented in French during the process in Canada and in Europe and discussed in LA Revue Canadienne de Psychiatrie (2011, 2019).
Figure 2. QAAPAPLE 1 and QAAPAPLE 2. LAI: Long Acting Injectable antipsychotic. (a) Short interval between injection; (b) long Interval between injection

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