Figures & data
Figure 1 (A) Time course of [E] and [Z] according to Equations (13) and (15) and from the numerical integration of the set of differential Equations 4-8. (B) Time course of [Z*] and [EI] [EI] according to Equations (16) and (18) and from the numerical integration of the set of differential Equations 4-8. The values of the equilibrium constants, rate constants and initial concentrations in (A) and (B) were: and
In each case the progress curves from the equation and from the simulation overlap in the scale used.
![Figure 1 (A) Time course of [E] and [Z] according to Equations (13) and (15) and from the numerical integration of the set of differential Equations 4-8. (B) Time course of [Z*] and [EI] [EI] according to Equations (16) and (18) and from the numerical integration of the set of differential Equations 4-8. The values of the equilibrium constants, rate constants and initial concentrations in (A) and (B) were: and In each case the progress curves from the equation and from the simulation overlap in the scale used.](/cms/asset/a1825125-2a81-4f8e-9ad1-a20baf6c1d83/ienz_a_211395_f0003_b.gif)
Figure 2 Time course of [E]a, according to Equation (19), for the same set of values of the equilibrium constants, rate constants and initial concentrations were the same as in Fig. 1.
![Figure 2 Time course of [E]a, according to Equation (19), for the same set of values of the equilibrium constants, rate constants and initial concentrations were the same as in Fig. 1.](/cms/asset/b74463d5-5b26-4d87-bead-c48fa2922362/ienz_a_211395_f0004_b.gif)
Figure 3 Effect of [I]0 on the time course of [E]a at fixed [Z]0- and [E]0-values according to Equation (19). For each progress curve the set of values of the equilibrium constants, rate constants, [Z]0 and [E]0 are the same as in Fig. 1. The [I]0-values used in the different progress curves were (mM): 0, 0.05, 1, 5, 10 and 50.
![Figure 3 Effect of [I]0 on the time course of [E]a at fixed [Z]0- and [E]0-values according to Equation (19). For each progress curve the set of values of the equilibrium constants, rate constants, [Z]0 and [E]0 are the same as in Fig. 1. The [I]0-values used in the different progress curves were (mM): 0, 0.05, 1, 5, 10 and 50.](/cms/asset/01a0fce3-c5d2-453f-b631-a8390e8a2833/ienz_a_211395_f0005_b.gif)
Figure 4 Effect of [E]0 on the time course of [E]a at fixed [Z]0- and [I]0-values according to Equation (19). For each progress curve the set of values of the equilibrium constants, rate constants, [Z]0 and [I]0 are the same as in Fig. 1. The [E]0-values used in the different progress curves were (nM): 0, 20, 40, 60, 80 and 100.
![Figure 4 Effect of [E]0 on the time course of [E]a at fixed [Z]0- and [I]0-values according to Equation (19). For each progress curve the set of values of the equilibrium constants, rate constants, [Z]0 and [I]0 are the same as in Fig. 1. The [E]0-values used in the different progress curves were (nM): 0, 20, 40, 60, 80 and 100.](/cms/asset/35501888-63c5-41db-9f5a-062fff763e2f/ienz_a_211395_f0006_b.gif)
Figure 5 Effect of [Z]0 on the time course of [E]a at fixed [I]0- and [E]0-values according to Equation (19). For each progress curve the set of values of the equilibrium constants, rate constants, [I]0 and [E]0 are the same as in Fig. 1. The [Z]0-values used in the different progress curves were (μM): 1, 1.05, 1.10, 1.20, 1.25 and 1.40.
![Figure 5 Effect of [Z]0 on the time course of [E]a at fixed [I]0- and [E]0-values according to Equation (19). For each progress curve the set of values of the equilibrium constants, rate constants, [I]0 and [E]0 are the same as in Fig. 1. The [Z]0-values used in the different progress curves were (μM): 1, 1.05, 1.10, 1.20, 1.25 and 1.40.](/cms/asset/0988097f-c13e-444c-a875-381b6ddb1963/ienz_a_211395_f0007_b.gif)