In vitro antifungal and antibacterial activities of extracts of Galium tricornutum subsp. longipedunculatum

Figures & data

Table I.  Antibacterial activity (Zone of inhibition in mm)* of the extracts and their fractions of Galium tricornutum subsp. longipedunculatum.

	E. Coli	B. subtilis	S. flexenari	S. aureu	P. aureu	S. typhi
Std	25	26	24	17	17	21
Cr^a	8	11	4	9	14	7
H^a	7	5	–	7	9	–
Cl^a	14	17	7	15	17	12
E^a	9	13	6	11	6	–
B^a	6	8	2	6	–	–
W ^a	–	5	–	–	–	–
Cr^f	6	8	–	6	–	7
H^f	–	–	–	–	–	–
Cl^f	11	13	–	2	–	–
W^f	4	9	–	8	–	8

* –no activity, 7–9 mm non significant, 17–18 mm (or above) significant, A aerial part, F fruit,Cr.crude fr., H.hexane fr., Cl.chloroform fr., E.ethyl acetate fr., B.butanol fr.,W.water fr.

Table III.  Antibacterial activity (MIC values in mg/mL) of the extracts and their fractions of Galium tricornutum subsp. longipedunculatum.

	E. Coli	B. subtilis	S. flexenari	S. aureu	P. aureu	S. typhi
Std.	0.0002	0.0005	0.0003	0.0009	0.0021	0.0014
Cr^a	0.66	0.53	0.98	0.59	0.31	0.83
H^a	0.69	0.94	100	0.66	0.58	>200
Cl^a	0.31	0.17	0.71	0.23	0.12	0.44
E^a	0.59	0.29	0.96	0.41	0.91	>200
B^a	0.92	0.63	100	0.87	>200	>200
W ^a	100	0.96	>200	>200	>200	>200
Cr^f	0.90	0.65	>200	0.91	100	0.61
H^f	>200	>200	>200	>200	>200	>200
Cl^f	0.54	0.39	>200	>200	>200	>200
W^f	1.18	0.61	>200	0.64	100	0.66

M = Miconazole, A = Amphotericin B,– no activity A.aerial part, F fruit, Cr.crude fr., H.hexane fr., Cl.chloroform fr., E.ethyl acetate fr., B.butanol fr., W.water fr.

Table II.  Antifungal activity (Zone of inhibition in mm)* of the extracts and their fractions of Galium tricornutum subsp. longipedunculatum.

	C. albicans	A. flavus	M. canis	F. solani	C. glabrata	T. longifusus
Std.	100^M	90^A	100^M	100^M	100^M	100^M
Cr^a	30	60	20	50	50	30
H^a	–	–	30	–	–	20
Cl^a	–	20	10	30	–	40
E^a	40	70	–	70	10	10
B^a	10	10	–	10	50	–
W ^a	–	20	–	–	40	–
Cr^f	–	20	10	–	10	–
H^f	–	–	–	–	–	–
Cl^f	–	–	–	–	–	–
W^f	–	30	20	–	20	–

* M = Miconazole, A = Amphotericin B,– no activity A.aerial part, F fruit, Cr.crude fr., H.hexane fr., Cl.chloroform fr., E.ethyl acetate fr., B.butanol fr.,W.water fr.

Table IV.  Antifungal activity (MIC values in mg/mL) of the extracts and their fractions of Galium tricornutum subsp. longipedunculatum.

	C. albicans	A. flavus	M. canis	F. solani	C. glabrata	T. longifusus
Std.	100^M	90^A	100^M	100^M	100^M	100^M
Cr^a	0.61	0.22	0.79	0.27	0.29	0.61
H^a	>200	>200	0.59	100	>200	0.77
Cl^a	>200	0.78	0.89	0.62	>200	0.53
E^a	0.54	0.18	>200	0.19	0.88	0.91
B^a	0.94	0.91	100	0.94	0.27	>200
W ^a	>200	0.76	>200	100	0.30	>200
Cr^f	>200	0.81	0.93	>200	0.86	>200
H^f	>200	>200	>200	>200	>200	>200
Cl^f	>200	>100	>200	>200	>200	>200
W^f	100	0.62	0.78	>200	0.79	>200

M = Miconazole, A = Amphotericin B,– no activity A.aerial part, F fruit,Cr.crude fr., H.hexane fr., Cl.chloroform fr., E.ethyl acetate fr., B.butanol fr., W.water fr.